Vibrating capsule helping constipation sufferers
‘It’s completely novel,’ says gastroenterologist
HOW PILL WORKS
Yishai Ron, the research leader and a gastroenterologist at the Tel-Aviv Sourasky Medical Center, said the capsule is designed to pulsate three times a minute, roughly the same pace the colon contracts to move waste products through. It starts vibrating 6-8 hours after being swallowed — roughly the time it takes for food to reach the lower part of the digestive system — so the vibrations are not perceptible, he said.
• Patients in the trial took the capsules twice a week for two weeks. It is too early to know how much the pills will cost or how long a patient would need to take the single-use capsules to clear up constipation.
Millions of people suffer from constipation — sometimes so bad it can go on for months or years. Medications are effective, but as many as half of all those with chronic constipation get little relief or suffer significant side effects, studies show.
Now an Israeli company, Vibrant, is testing a capsule that would vibrate in the colon, rather than deliver medications.
Adding movements inside the lower intestine mimics peristalsis, the biological process that pushes waves of waste through the bowel. The researchers hope it will break up clumps of waste and encourage the system to work more normally.
They have only just begun to test the multivitamin-sized pill, releasing results Saturday showing it was safely tested in 26 patients who have bowel movements just twice a week on average.