The U.S. Is Botching the Zika Fight A genetically tweaked mosquito could stop the illness, but regulators won’t test it. Why would that be? By John J. Cohrssen and Henry I. Miller
http://www.wsj.com/articles/the-u-s-is-botching-the-zika-fight-1457907116?cb=logged0.45084601382469314
Almost every day seems to bring more bad news about the Zika virus: babies born with malformed brains; adults suffering the progressive paralysis of Guillain-Barré syndrome; Americans diagnosed after traveling to the tropics; active transmission of the disease in U.S. territories. Several companies are working on a vaccine, but primarily because of regulatory requirements none is likely to become commercially available before the end of the decade.
Last month President Obama announced that he will ask Congress for $1.8 billion to fight the mosquito-borne disease. But the president seems unaware that the bumbling of his Food and Drug Administration is blocking progress on a vital tool to control the Aedes aegypti mosquitoes that carry and transmit Zika and the viruses that cause dengue fever, chikungunya and yellow fever.
Using genetic engineering techniques, the British company Oxitec (a subsidiary of American-owned Intrexon) has created male Aedes aegypti mosquitoes with a specific mutation that causes them to need a certain chemical (the antibiotic tetracycline) to survive. Without it, they die—and their offspring die before reaching maturity. Releasing the males over several months causes a marked reduction in the mosquito population. Because male mosquitoes don’t bite, they present no health risk, and, because their progeny die, no genetically engineered mosquitoes persist in the environment.
This approach has already been widely and successfully tested abroad. Brazil has approved it, and Oxitec is helping to control mosquitoes in the city of Piracicaba. But in the U.S. the FDA has been paralyzed, unwilling to permit even small-scale testing. How did the feds go wrong? CONTINUE AT SITE
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