I missed last week’s good news from Israel. In an avalanche of grim world news, it is heartening to know how Israel’s outsize contributions to every aspect of human endeavor bring succor to those struggling with the ravages of illness, famines, epidemics, and wars…..rsk
https://verygoodnewsisrael.blogspot.com/
ISRAEL’S MEDICAL ACHIEVEMENTS
Stopping cancer spreading during chemotherapy. A Technion doctorate student has discovered that the LOX enzyme plays a major role in helping cancer spread (metastasis) when the patient is having chemotherapy. Inhibiting LOX protects the patient from this deadly effect.
https://www.technion.ac.il/en/2022/02/world-cancer-day-chemotherapy-metastasis/
https://pubmed.ncbi.nlm.nih.gov/34666995/
Hope for when cancer has spread. Israel’s New Phase has developed hyperthermic treatment that kills up to 50% of metastatic cancer. In animal and human trials, iron-oxide nanoparticles, produced in a lab managed by three Druze Arab women, are injected into stage 4 cancer patients, and then heated to 45º C using RF radiation.
https://www.israel21c.org/novel-hyperthermic-treatment-offers-hope-for-stage-4-metastatic-cancer/
https://newphase.co.il/ https://www.youtube.com/watch?v=BZ6h6szr4eM
Prostate cancer treatment is saving lives. (TY Don) Although not an Israeli treatment, Israel’s Sheba Medical Center is one of the few global hospitals treating prostate cancer patients with Lutetium-177 therapy. It attaches to prostate-specific membrane antigens (PSMAs) on tumors and emits beta radiation to neutralize them.
https://www.shebaonline.org/how-does-lutetium-177-therapy-work/
We have the cure inside us. Scientists at Israel’s Technion Institute have found that misfolding proteins in the brain cells of ALS and Huntingdon’s sufferers can be corrected by other proteins already in the cell, called “chaperones”. But the cell doesn’t activate them or activates the wrong ones! New treatments are anticipated.
https://www.technion.ac.il/en/2022/02/huntingtons-als-chaperone/
https://www.nature.com/articles/s41467-022-27982-w
Longer-lasting heart valves. An Israeli-led team of researchers has prevented the deterioration of bioprosthetic heart valves (of animal origin). These last only 10 years due to calcification of the tissues. They used hearts from pigs that were engineered to stop expressing foreign sugars and this prevented calcification.
https://www.nature.com/articles/s41591-022-01682-w
Repairing heart valves without replacing. The calcification of heart valves is currently resolved by transplanting a new prosthetic valve (see above). Israel’s Pi-Cardia (see here previously) has been developing the Leaflex system to treat the calcification, and is currently conducting human clinical trials across Europe.
https://www.israel21c.org/novel-non-surgical-solutions-for-aortic-valve-stenosis/
https://www.youtube.com/watch?v=5NXQQ-Zqnes
Gut bacteria could prevent heart attacks. Scientists from Israel’s Rabin Medical Center and the Weizmann Institute studied the microbiome of 200 patients just hours after a heart attack. They found most were missing a Clostridiaceae family bacterium that was present in a control group. They are now isolating it into pill form.
https://www.timesofisrael.com/israeli-study-mines-donor-poop-for-bacteria-that-could-avert-heart-attacks/
https://www.nature.com/articles/s41591-022-01686-6
Helping preemies absorb food. The ELGN-GI insulin formulation developed by Israel’s Elgan can save the lives of preterm babies with immature stomachs that cause feeding intolerance. It will avoid the adverse effects of intravenous nutrition, which often leads to infection and liver problems. A Phase 3 trial is being planned.
https://www.jpost.com/health-and-wellness/pregnancy-and-birth/article-699123 https://www.elganpharma.com/
http://www.ngt3vc.com/elgan-pharma/
A physical therapist on your smartphone. Israel’s OneStep uses the power of the smartphone to analyze gait (how you walk) and provide feedback directly to patients and their physical therapists. OneStep is partnering with Kinomatic in the US to bring OneStep’s app to all patients using Kinomatic’s Virtual Reality solution.
https://www.prnewswire.com/il/news-releases/digital-physical-therapy-company-onestep-partners-with-smart-surgery-provider-kinomatic-to-enhance-physical-therapy-for-surgery-patients-301477411.html
https://www.onestep.co/ https://www.youtube.com/watch?v=335FEpK2y7Y
Successful trials for portable eye test. Israel’s AEYE Health (see here previously) has just completed Phase 3 clinical trials of its hand-held retinal analysis system. The hand-held fundus camera and single-image AI software detected diabetic retinopathy with high accuracy, far better than current expensive specialist cameras.
https://www.timesofisrael.com/spotlight/seeing-straight-with-the-help-of-artificial-intelligence/
The best partners for innovation. Israel’s Sheba Medical Center has again been ranked as the 10th best hospital in the world by Newsweek Magazine. Sheba also announced a partnership with GE Healthcare to develop digital healthcare solutions in cardiology, remote pregnancy monitoring and molecular imaging.
https://www.israelnationalnews.com/news/323198
https://www.jns.org/israels-sheba-ge-team-up-to-advance-digital-healthcare/
Global DNA sequencing center. Illumina – the world’s leading DNA sequencing company, worth over $50 billion, is opening a Center of Excellence in Tel Aviv. It will develop Artificial Intelligence (AI) solutions that dramatically shorten genome analysis time for diagnosing rare diseases and transform lives.
https://www.calcalistech.com/ctechnews/article/ryfdj7ce5
Advanced Materials. Several issues of the international journal Advanced Materials, including cover pages, feature the breakthrough skin patches developed in the lab of Israel’s Technion Arab Professor Hossam Haick (see here previously). They include Strain sensors, Wound dressing (and cover), Micro-needles sensor, Electronic skin and more. https://www.technion.ac.il/en/2022/02/hossam-haick-diagnosis-micro-needles/