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MEDICINE AND HEALTH

Drug shortages upend hospitals care, cancer treatments Tina Reed

https://www.axios.com/2023/03/21/drug-shortages-upend-cancer-treatments

Supplies of some essential drugs used in hospitals are hitting 10-year lows, forcing rationing and pharmacy workarounds.

Driving the news: Drug shortages are the worst they’ve been in a decade, according to the American Society of Health-System Pharmacists — a sign of how much we rely on low-margin manufacturers with limited capacity for basics like the inhalation drug albuterol and some common cancer treatments.

What they’re saying: Quality control issues, selected plant closures and other manufacturing woes have added up, Michael Ganio, senior director of pharmacy, practice and quality at ASHP told Axios.

Between the lines: Oncology drugs have been hit particularly hard in recent months, putting experts on high alert.

Those in short supply include methotrexate, an injectable chemotherapy drug, and one of several generics produced by Illinois-based Akorn Pharmaceuticals, which shuttered operations last month due to bankruptcy.
Manufacturing delays and increased demand have also led to shortages of the cancer treatments cisplatin, and fluorouracil, per ASHP.
Pluvicto — used to extend survival among patients with metastatic prostate cancer — will take months to be made available to patients again, the Wall Street Journal reports.
“People will die from this shortage, for sure,” Jonathan McConathy, director of the division of molecular imaging and therapeutics at the University of Alabama, told WSJ.
A survey of health systems conducted by the group End Drug Shortages Alliance found the injectable Bacillus Calmette-Guerin (BCG), used for treating bladder cancer, was being rationed or was not available for use at all.
“This is a terrible crisis. We should be doing everything we can to give every single one of these patients the best chance of survival,” Laura Bray, a board member of the alliance, told CNN.

Between the lines: Manufacturing delays and quality problems are blamed for the shortages. But that’s often because there aren’t many alternative sites to pick up the slack in the system due to the challenging economics of the market, experts say.

Doctors Are Losing Their Calling The sanctity of the medical profession has been lost to corporate centralization and burnout. By Michael P.H. Stanley

https://www.wsj.com/articles/doctors-are-losing-their-calling-union-mass-general-brigham-resident-suicide-depression-representation-burnout-7f72ab6?mod=opinion_lead_pos8

Physician-trainees at Mass General Brigham are attempting to unionize. If they succeed, the union would be the largest of its kind in the country with more than 2,500 members, joining the estimated 15% of U.S. medical trainees who’ve assembled under the Committee of Interns and Residents in recent years. At the center of the doctors’ unionization efforts is a desire to reclaim their identity as service-driven providers and to fight for the autonomy and fair working conditions that they’ve lost as their profession becomes more commercialized and centralized.

Doctors are proud of their occupation’s mixture of sacrament and science in service to society. Urbanely trained at universities, these learned professionals once left the city to settle into solo practices or small partnerships in the towns they served. This autonomy allowed them to charge patients what they could afford—some more, some less and some not at all. Meanwhile, their authority allowed them to advocate effectively on behalf of their patients, even on nonmedical matters. Their familiarity with their neighbor-patients encouraged participation in the community, both economically and socially.

But as teaching hospitals were subsumed into larger corporate systems, and healthcare grew more expensive from the mid-20th century onward, hospital systems lobbied for policies that created a regulatory environment too thick and expensive for private practitioners to remain solvent. For doctors, hospital-acquired practices held the promise that as employees they could forget about red tape and bottom lines because the hospital would handle it. Doctors would purportedly get to focus on practice instead of administrative tasks.

Israeli researchers discover breakthrough in pancreatic cancer treatment: Team of scientists led by researchers from Hebrew University discover way to prevent pancreatic cancers from metastasizing.

https://www.israelnationalnews.com/news/369093?utm_source=activetrail&utm_medium=email&utm_campaign=nl

In a new study published today in the journal Nature, a team of scientists led by researchers from the Hebrew University of Jerusalem discovered that changes in the processing of RNA molecules – and not genetic changes in the DNA – drive pancreatic ductal adenocarcinoma (PDA) tumors to become metastatic.

This multinational study was conducted in collaboration with Sheba Medical Center and Bar Ilan University in Israel, Cornell University and Cold Spring Harbor Laboratory in the United States, and Toronto University in Canada. The study was led by doctoral student Amina Jbara of Professor Rotem Karni’s research group at the Hebrew University Faculty of Medicine.

Evaluating roughly four hundred PDA tumor samples, both non-metastatic and metastatic, the researchers discovered that a central protein that controls RNA processing, RBFOX2, is degraded and present in much lower levels in metastases.

“Our unique findings demonstrate that the disappearance of RBFOX2 protein causes hundreds of genes to produce RNAs and proteins in a different way, which contributes to the invasive capabilities of the cancer cells,” Professor Rotem Karni explained. “We found that restoring RBFOX2 to PDA metastatic cells inhibits the formation of metastases, while the elimination of RBFOX2 in non-metastatic PDA cells stimulates the formation of pancreatic cancer metastases.”

SEE THIS GREAT VIDEO OF FAUCI GETTING TOLD OFF!!!!

https://www.americanthinker.com/blog/2023/03/epic_video_informed_black_guy_on_dc_street_destroys_fauci_to_his_face.html

Epic video: Informed black guy on DC street destroys Fauci to his face By Ben Bartee

I don’t know how this clip slipped past me, but a video has resurfaced of Anthony Fauci and Washington, D.C. mayor Muriel Bowser canvassing the streets to encourage the urban population to get vaxxed and filming it for propaganda purposes.

First, some background, via East of the River:

Fairlawn residents answered their door Saturday morning to find some surprise guests on the front stoop: Dr. Anthony Fauci and Mayor Muriel Bowser (D).

The two spent an hour and a half canvassing the neighborhood as part of the DC COVID-19 Community Corps Day of Action.

“Oh my god, it’s Dr. Fauci!” one woman screamed as she opened the door. “I’d come give you a kiss, but I’ve got a cold on.” The woman, who was already vaccinated, blew him a kiss from the top of the stairs instead. “Y’all see Dr. Fauci over here?” she called to her neighbors.

Another woman told Dr. Fauci that she hadn’t gotten the vaccine because she was worried she would contract the virus and then convey it to her children, who are not yet eligible to get the vaccine.

“You should get it then, because not only would it protect you, but then you’d protect your whole family,” Fauci said. “If you were to get infected, you could pass it on to them, but if you get vaccinated, you’re not going to get infected. Want to do it today?”

Their photo op was totally ruined by a poorly-conceived interaction with one resident, who not only expressed no interest in getting injected but destroyed the entire narrative right to Fauci’s face with a tenacity never duplicated in any media interview that I’ve ever seen (the handpicked “journalists” permitted to interview Fauci being heavily vetted beforehand).

The “Trans Child” Is the New Totem of the American Left Christopher Rufo

https://rufo.substack.com/p/the-trans-child-is-the-new-totem?utm_source=substack&utm_medium=email

Joe Biden recently proposed in an interview that he would support federal legislation to force states such as Florida, Texas, and Tennessee to allow doctors to perform hormone therapies and sex change operations on children. This is all under the rubric of a deeply misleading term, “trans-affirming care,” that has become a deep conviction on the political Left. I’d like to analyze the clip in which Biden is talking about this and show that, for the Left, the so-called “trans child” serves almost as a religious totem. Let’s take a listen.

[President Biden:] Transgender kids is a really harder thing. What’s going on in Florida is, as my mother would say, “close to sinful.” It’s just terrible what they’re doing. It’s not like a kid wakes up one morning and says, “You know, I decided I want to become a man” or “I want to become a woman” or “I want to change.” I mean, what are they thinking about here? They’re human beings. They love, they have feelings, they have inclinations that are, I mean, just to me is, I don’t know. It’s cruel. And the way we do it is we make sure we pass legislation like we passed on same-sex marriage. You mess with that, you’re breaking the law and you’re going to be held accountable.

Let’s break that down. In a certain sense, Biden’s comment sounds reasonable, it sounds humane, it sounds fairly rational. But this is all based on manipulative language and a hidden ideology that operates under the surface.

First, the category “transgender kids”: that’s the first thing he says and he lays down the marker that that’s the category we’re talking about. But as my friend and colleague Colin Wright has pointed out, there’s no such thing as a “transgender kid.” And what Wright means by that is that a child is not innately transgender, but becomes transgender once the child enters the process of medicalization—hormones, surgeries, and other medical interventions. It’s not that they cannot have feelings of discomfort or dysphoria—that’s certainly true—but they only become transgender when adults intervene. These are parents, doctors, and psychotherapists, and then that child is put on Lupron, put on testosterone or estrogen, has the double mastectomy, or gets the penile inversion surgery.

Florida Protects Minors from Gender Reassignment Medical Procedures And the Left descends into TOTAL MELTDOWN. by Joseph Klein

https://www.frontpagemag.com/florida-protects-minors-from-gender-reassignment-medical-procedures/

The Florida Board of Medicine has put into effect a new rule prohibiting the use of puberty blockers, hormone therapies, or gender reassignment surgeries for minors under the age of 18 who say they want to change their gender identities. Trans activists and their supporters inside and outside of the medical field describe such transgender medical procedures as part of “gender-affirming care.”

Florida lawmakers are considering legislation that would codify these bans into law and make it a felony to provide any such so-called “gender-affirming” medical care to minors before their eighteenth birthday.

Left-wing progressives are in an uproar. Florida’s equivalent of New York Rep. Alexandria Ocasio-Cortez, Democratic State Rep. Anna Eskamani, accused Florida’s Governor Ron DeSantis of “erasing our trans babies” at a boisterous rally in Florida’s Capitol protesting the bans. “We are facing a governor who wants to commit genocide on trans people,” she said.

These are the words of an uncompromising pro-abortionist.

The transgender ideologues’ hysteria extends to the Biden administration.

“This is the first time I have seen a medical board weaponized against medical providers that are providing evidence-based, standard of care treatment,” said President Biden’s Department of Health and Human Services’ Assistant Secretary Rachel Levine, who is transgender.

Rachel Levine appeared recently at Connecticut Children’s Hospital, praising medical procedures for changing children’s gender and declaring that such medical procedures have the “highest support” of the Biden administration. “President Biden supports you. I as the Assistant Secretary for Health will support you and I talk about this topic, everywhere I go, to get the word out,” Levine said.

Fauci B.C. Long before COVID, the seeds of the pandemic were already in the ground. By Lloyd Billingsley

https://amgreatness.com/2023/03/19/fauci-b-c/

The FBI has for quite some time now assessed that the origins of the pandemic are most likely a potential lab incident in Wuhan,” explains FBI Director Christopher Wray. “Here you are talking about a potential leak from a Chinese government-controlled lab,” and from the first case of COVID-19 in the United States in January 2020, adds Wray, China has tried to “thwart and obfuscate” investigations into the origin of the pandemic.

Last month, the U.S. Department of Energy concluded that the COVID-19 pandemic began with a leak from a laboratory in China. But Dr. Anthony Fauci didn’t think so. 

While repeating the claim that he has an open mind, Fauci sticks to the natural origin theory and charges that his critics, especially those who have called for him to be prosecuted, are “off the deep end.” That invites a deep dive on Fauci, all the way to the bottom. 

Born in 1940, Anthony Fauci earned a medical degree in 1966 but if he ever practiced medicine it was only for a short time. In 1968, to avoid treating wounded GIs in military hospitals, Fauci took a cushy “yellow beret” job with the National Institutes of Health. Fauci’s bio showed no advanced degrees in biochemistry or molecular biology, but in 1984 the NIH made Fauci director of the National Institute of Allergy and Infectious Diseases (NIAID).

Back in the 1990s Nobel laureate Kary Mullis, inventor of the polymerase chain reaction (PCR),  said Fauci “doesn’t understand electron microscopy and he doesn’t understand medicine. He should not be in a position like he’s in.” In other words, Fauci was unqualified, and it showed in his handling of AIDS.

French medical scientist Luc Montagnier, a Nobel laureate, discovered the human immunodeficiency virus (HIV), which Fauci claimed was the sole cause of AIDS.  HIV, Fauci claimed,  overexcites some immune signaling pathways, while eluding the detection of others. And though the main target of the virus appears to be the famed helper T-cells, or CD-4 cells, which it can infiltrate and kill, the virus also ends up stimulating the response of other immune cells so inappropriately that they eventually collapse from overwork or confusion.

Ban Transgender Operations on Children What ethical consent can be given for lifelong harm? by John and Andy Schlafly

https://www.frontpagemag.com/ban-transgender-operations-on-children/

An emergency appeal reaches the U.S. Supreme Court from West Virginia, which is trying to safeguard girls’ sports teams against biological males pretending to be girls. A well-reasoned federal district court decision upheld its law against a constitutional challenge on behalf of an 11-year-old, a majority-Democrat panel on the Fourth Circuit suspended the good law.

This case is being called the most important yet in the transgender movement, which is suddenly invading nearly every school and government program. Chief Justice John Roberts ordered a response to West Virginia to be filed by noon next Monday, March 20, and already amicus briefs in support of West Virginia’s necessary law have been filed.

The lower federal courts held that transgenders are entitled to a heightened form of protection under the Constitution, and that issue is now before the Supreme Court. Two years ago, the Supreme Court ducked a case concerning an attempt by a school board to keep biological boys and girls out of each others’ restrooms.

In that lawsuit arising from Gloucester High School in Virginia, the Supreme Court denied a petition for certiorari on this issue of forcing transgenderism on schools. That handed transgender activists a victory by leaving intact the Fourth Circuit ruling against the school board, which declared transgender conduct to be a new constitutional right and a Title IX federal right in schools.

Aided by desires to attract attention, hordes of children are declaring an interest in being transgender now. Last month it was reported that several 5th graders told their teacher that they wanted to become transgender, and when the teacher asked the Washington University Transgender Center at St. Louis Children’s Hospital for advice its response was to affirm the behavior, without suggesting that the parents be informed.

How Dr. Fauci Shaped the COVID-19 Narrative And the question remains: why? by Jeffrey Gunter

https://www.frontpagemag.com/how-dr-fauci-shaped-the-covid-19-narrative/

We now know what we always suspected in the beginning. The Covid-19 virus was leaked from a lab in Wuhan that caused chaos worldwide. The death and destruction of Covid-19 was used as a political weapon and millions of lives were lost in the process. President Trump called it in the very beginning. He instinctively knew the origin behind the virus, and he was fearless in presenting this truth to the American people.

According to a memo released by the House Select Subcommittee on the Coronavirus Pandemic, Fauci not only waved away concerns that the virus was a lab leak, knowing this was not the case, but also paved the way for ridicule and punishment of anyone would push back on his “faux medical propaganda campaign.”

The revelations revealed by the Congressional Subcommittee investigating the origins of the Covid-19 pandemic showed that the misinformation surrounding the lab theory and blatant suppression was intentional. CNN suppressed this. Dr. Fauci suppressed this. In so doing,

Fauci lied to those he swore to take care of, namely the American people.

The reports now clearly show that the media’s most beloved, Dr. Fauci, commissioned the “Proximal Origins” paper, to dismiss the theory that the virus originated from a lab in Wuhan. Fauci desperately used a premier scientific journal, “Nature” to spread his lies, while thousands of Americans were dying around the country.

Liz Peek: Unrepentant US health agencies issue more bizarre directives

https://thehill.com/opinion/healthcare/3893118-unrepentant-us-health-agencies-issue-more-bizarre-directives/

You might think U.S. health authorities would be embarrassed. After all, the Center for Disease Control and Prevention (CDC), the National Institutes of Health (NIH), the Food and Drug Administration (FDA) and other agencies oversaw policies that produced more COVID-19 deaths per capita than nearly any other developed country.

More humiliating, they earned that distinction while dictating draconian shutdowns and school closures that profoundly damaged our economy and our children’s educations. And even though Americans had early access to the world’s best vaccines.

You would be wrong. Instead of adopting a humbler or more cautious approach to managing the waning virus, the CDC and the Biden administration are more truculent – and incomprehensible – than ever.

Most recently, the Biden White House has doubled down on not allowing Novak Djokovic into our country because the world’s top tennis player is not vaccinated. The tennis star was similarly prevented from coming to the U.S. last year, causing him to miss out on playing in the prestigious U.S. Open and for a brief period leading to his losing his number one status.

At the same time, the White House is set to announce that people coming to the U.S. from China will no longer need a negative COVID test to gain entry. Neither policy makes sense.

The Djokovic decision seems bizarre, especially given what we know about the vaccines and their impact over time. The vaccines’ efficacy declines rapidly, meaning that booster shots are needed to revive its protections and to address today’s most prevalent variants.

One study of veterans showed that the protection derived from the Johnson & Johnson vaccine (admittedly, the worst) dropped from 86 percent in March 2021 to 13 percent in September, just six months later.