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MEDICINE AND HEALTH

Authoritarian Science and the Case of Hydroxychloroquine The approach to medical information increasingly taken by authorities and the media is damaging to public health and scientific inquiry. Connor Harris

https://www.city-journal.org/hydroxychloroquine-and-authoritarian-science

Imperial County, California, a poor, largely Hispanic agricultural region in the southeastern corner of the state, has been hit hard by Covid-19. By the end of January, according to the New York Times’s Covid-19 database, Imperial County had suffered 845 Covid deaths, or 4.7 per thousand inhabitants—a rate almost 80 percent higher than the U.S. average. The case fatality rate in Imperial County is 1.44 percent, the second-highest in California—and was significantly higher, 2.10 percent, at the end of October 2021 before the Omicron wave.

Two doctors in Imperial County, though—George Fareed and Brian Tyson, who run the All Valley Urgent Care network of medical centers—claim to have done far better with their Covid-19 patients. In fact, they claim near-perfect success: in a book that they published last January, they claim to have seen more than 7,000 patients and had only three deaths, all among patients who began treatment in later disease stages. A statistical analysis of part of their results by the statistician Mathew Crawford, included in their book, counts only seven hospitalizations and three deaths among 4,376 patients seen up through March 13, 2021—a reduction in hospitalization risk of well over 90 percent from the county average, even after (admittedly imperfect) statistical adjustments for differences in age between Fareed and Tyson’s patients and the general population.

According to prevailing medical views, Fareed and Tyson’s claimed results should be impossible. The doctors’ first protocol was based around hydroxychloroquine (HCQ), a repurposed anti-malarial drug, with other drugs such as ivermectin as more recent additions. Received opinion on the drugs is that ivermectin is at best unproven in treating Covid-19 (the Food and Drug Administration maintains an official webpage warning against using it as a treatment for the virus), and that HCQ has been actively disproved: early optimism from laboratory experiments and small clinical studies did not hold up in larger, more rigorous trials.

Fauci’s War on His AIDS Critic And the collateral damage for today. Lloyd Billingsley

https://www.frontpagemag.com/fpm/2022/02/faucis-war-his-aids-critic-lloyd-billingsley/

Peter Duesberg, former professor of molecular and cell biology at UC Berkeley, turned 85 in December and hasn’t been picking up the phone or answering email. Fortunately, professor Duesberg’s experiences with Dr. Anthony Fauci are already on record, with insight for embattled Americans in 2022.

“The 71-year-old Duesberg could pass for a younger man,” noted Jeanne Lenzer in Discovery Magazine back in 2008. “AIDS ‘Dissident’ Seeks Redemption … and a Cure for Cancer,” proclaimed the headline on the 5,406-word article, with the subhead explaining, “Biologist Peter Duesberg was all but banished from science for his views on HIV.”

Born in Münster, Germany, in 1936, Duesberg earned a PhD in chemistry from the University of Frankfurt in 1963. The next year he arrived at UC Berkeley as a postdoctoral fellow “hoping to unlock the secrets of cancer” and joining the hunt for retroviruses. In 1986, at age 49, Duesberg was elected to the National Academy of Sciences and given a National Institutes of Health Outstanding Investigator Award, as Lenzer noted, “one of the most prestigious and coveted grants.”

Duesberg knew that retroviruses don’t kill the host cells they infect, so he was skeptical when HIV was proclaimed to be the cause of AIDS, with no scientific study making the case. In March of 1987, Duesberg published a paper in Cancer Research questioning the role of HIV as the cause of AIDS. As Lenzer noted, the man colleagues might once have regarded as the “Einstein of biology” was then smeared as an AIDS “denier,” but there was more to it than name-calling.

License to Misinform Gavin Newsom defends California’s lockdown policies with dodgy data. Kerry Jackson

https://www.city-journal.org/gavin-newsoms-license-to-misinform-on-covid

Last summer, while trying to survive a recall effort, California governor Gavin Newsom claimed that Texas middle-class families “pay more taxes than middle-class families in California” and challenged doubters to “look that up.” A few months later, he swore that “violent crime and property crime” is “higher in Texas than in California.”

The facts didn’t land on his side. Comparisons showed that taxes are a greater burden in California, and there’s little difference in crime between the states in recent years.

Because Newsom is a media darling, his exaggerations didn’t hurt him politically. So he’s free to continue to dish out misinformation. “We’d have 40,000 more Californians dead” if he had followed Florida governor Ron DeSantis’s approach to the pandemic, Newsom said last month while appearing on ABC’s The View. Though Newsom seems to have pulled that 40,000 number out of the ether, it is true that California did do a little better than Florida when looking at Covid deaths per 100,000 residents (California’s number currently stands at 110, against Florida’s 128—both of which are below the national average of 138). But if he believes that his lockdown regime was the reason for California’s lower rate, he’s deluding himself.

A year ago, one media outlet called California “the most locked down state across the country,” and San Diego County “the most locked down county in the state, with Los Angeles County about the same.” It might be hard to recall now, but California was the first state to shut down its economy and movement of people, and it appears that it will be the last to restore those lost liberties. While Newsom and other public officials were telling Californians that they were better off hiding under their beds, people were “flocking to Florida to find freedom, as other states and countries continue to keep their citizens locked down,” according to the James Madison Institute. In the spring of 2020, while Newsom was increasing his powers through executive orders, making a dodgy $1 billion mask deal with a Chinese company, and holding his made-for-TV performances every day at noon, DeSantis was already easing restrictions. By September of that year, all statewide rules in Florida were gone, never to return.

ITS TIME TO ASK: WERE ANY OF THE COVID LOCKDOWNS. MANDATES, CLOSURES WORTH IT?

https://issuesinsights.com/2022/02/11/its-time-to-ask-were-any-of-the-covid-mandates-closures-lockdowns-worth-it/

With COVID deaths now topping 910,000, the Biden administration and the rest of the Democratic left are deciding to ease up on their mandate regime. We need to learn to live with COVID, they say – repeating advice President Donald Trump issued back in October 2020.

We’re all for ditching the left’s COVID police state, even if Democrats’ reason is political, as we pointed out in this space yesterday.

But that leaves us with a question: Was any of it worth it? Did any of the guidelines, mandates, orders, shutdowns, cancelations, lockdowns do anything to alter the course of the disease, or change in any way the number of people who died from it?

Was it worth the massive disruption to our jobs and lives, the education losses suffered by our children, the trillions in debt piled up? Was it worth shutting down dissent by Tech Giants? Or the unleashing of mask scolds? Or vaccine passports? Or the divisiveness all of it fueled?

After all, even with all that in place, Centers for Disease Control data show that more than 77 million Americans have contracted COVID, and 910,373 deaths are linked to the disease.

What would have been different if we’d done nothing, other than encourage people to use common sense?

The Next Pig Thing in Medicine A man is still alive a month after a pig heart transplant. By Sally Satel

https://www.wsj.com/articles/pig-medicine-organ-donation-kidney-heart-transplant-xenotransplantation-end-state-renal-disease-medicare-11644439815?mod=opinion_lead_pos11

I had my first kidney transplant in 2004. It gave out after 10 years. The replacement, which I received in 2016, functions well but won’t last forever. “May your organ outlive you,” older transplant patients tell each other. Otherwise, you may not survive the queue for a new one.

That’s why recent breakthroughs in xenotransplantation—the implantation of animal tissues and organs across species—have been exhilarating. In September, doctors at NYU Langone Medical Center attached a pig kidney to blood vessels in a dead woman’s leg (with her family’s permission). It produced urine and cleared waste products during the 54-hour observation period. Two months later, they repeated the procedure.

Also in September, a team at the University of Alabama at Birmingham implanted the first-ever genetically modified pig kidneys into the body of Jim Parsons, 57, of Huntsville, who had been left brain-dead by a motorcycle accident. The new kidneys turned “beautiful and pink,” the lead surgeon said. The experiment lasted 77 hours.

Then, on Jan. 7, surgeons at the University of Maryland transplanted a heart from a genetically modified pig into David Bennett Sr. , who doctors said had exhausted all other treatment options. Mr. Bennett, 57, is still alive.

More than 90,000 Americans are waiting for a kidney. In 2021 fewer than 25,000 received one, and some 41,000 were added to the national waiting list. On the average day, around a dozen people on the list die.

COVID CRUELTY

https://issuesinsights.com/2022/02/09/covid-cruelty/

It’s been said that a crisis doesn’t create character, it reveals it. Far too often, the pandemic has shown that many Americans in positions of authority are of poor character. At least we know who the sadists are, since they so helpfully identified themselves.

The line between being overly cautious and just plain cruel has been crossed repeatedly. This is where we are today in what had previously been thought of as civilization:

Hospitals across the country are removing unvaccinated organ transplant patients from waiting lists. Medical ethicists are fine with this, because the patients need to be protected from illnesses while their bodies accept the new organs, and they are prioritized based on their chances of survival. These “ethicists,” however, come off as vindictive, “othering” the unvaccinated in line with the narrative. Moving these patients lower on the list based on a risk they assume seems acceptable, dropping them altogether is not. It’s intentionally punitive and ghoulish. The decisions reinforce, as well, the naked fact that the vaccine mandates are authoritarian power plays.
A Virginia hospital that refused to provide Ivermectin prescribed by a doctor to a dying COVID patient was found in contempt of court before it finally relented and allowed the drug to be administered. It was too late, though. The woman died five days after the judge’s ruling.