New Israeli Drug for Crohn’s Disease ‘Groundbreaking’ By Tyler O’Neil

https://pjmedia.com/trending/new-israeli-drug-for-crohns-disease-groundbreaking/

On Sunday, an Israeli drug company announced that a cure for Crohn’s disease may be in the works. As results of a massive study on the effectiveness of a potentially life-saving drug come in, RedHill Biopharma has also filed new patents for it in the U.S. and Europe.

“This is a groundbreaking new approach, and if we’re correct this will be a new salvation for patients and for doctors and for everyone affected by this disease,” Guy Goldberg, chief business officer at RedHill, told ILTV Israel on Sunday. “We are right now conducting probably the largest most robust study ever done with an anti-bacterial approach to treating Crohn’s disease.”

Crohn’s disease is an inflammatory bowel disease in which the body’s immune system attacks the gastrointestinal tract from mouth to anus. Signs and symptoms include abdominal pain, diarrhea, fever, and weight loss, while complications include anemia, skin rashes, arthritis, inflammation of the eye, and tiredness.

The direct cause of the disease remains unknown, but it seems linked to a combination of environmental, immune, and bacterial factors in people with a certain type of genetics. About half of the overall risk is related to genetics, with more than 70 genes involved. Tobacco smokers are twice as likely to develop the disease. There is as yet no cure, and people with Crohn’s disease have a reduced life expectancy.

Approximately 1.5 million people were diagnosed with Crohn’s disease worldwide in 2017, and global sales of Crohn’s disease therapies are estimated to exceed $10 billion in 2018, according to RedHill’s research.

“The current way of treating Crohn’s disease is basically suppressing the body’s entire immune response and that only works for a temporary period of time and it has very serious side effects,” Goldberg explained. “They’re essentially treating the symptoms of the disease and not providing a cure.”

By contrast, RedHill is “trying to address the underlying cause of the disease,” Following the theory that it is caused by a bacterial infection involving Mycobacterium avium subspecies paratuberculosis (MAP).

That’s why the RedHill study is so important. The Israeli company is currently conducting a first Phase III study of the drug RHB-104 among Crohn’s disease patients. The last patient in the study completed 26 weeks of treatment in early May 2018, and results from the study are expected in the coming weeks.

The study is a randomized, double-blind, placebo-controlled study evaluating the safety and efficacy of RHB-104 in subjects with moderately to severely active Crohn’s disease. The goal is disease remission, and the study has enrolled 331 patients in the U.S., Canada, Europe, Australia, New Zealand, and Israel. CONTINUE AT SITE

Schumer: Trump Chose Kavanaugh as Insurance against Mueller Investigation By Mairead McArdle

https://www.nationalreview.com/news/chuck-schumer-donald-trump-chose-brett-kavanaugh-as-insurance-against-mueller-investigation/

Senate minority leader Chuck Schumer said on Tuesday that President Trump nominated Judge Brett Kavanaugh to fill Justice Anthony Kennedy’s seat on the Supreme Court because the president is “worried” about Robert Mueller’s Russia investigation.

“Why did the president stick with Kavanaugh? Because he’s worried that Mr. Mueller will go to the court and ask that the president be subpoenaed,” the New York Democrat said, flanked by other Senate Democrats outside the Supreme Court. “And President Trump knows that Kavanaugh will be a barrier to preventing that investigation from going there….His views on this issue are more extreme than just about anyone else on that list.”

Trump announced Kavanaugh’s nomination Monday evening, after which a slew of Senate Democrats pledged to oppose his confirmation.

Democrats are most worried about the conservative, Catholic federal appellate judge’s potential to help overturn Roe v. Wade, the 1973 case which established a constitutional right to abortion, but they have also sounded the alarm about Kavanaugh’s views on presidential indictment.

The Strange Career of White Privilege By Victor Davis Hanson

https://www.nationalreview.com/2018/07/strange-career-of-white-privilege/

Rich whites invent minority pedigrees to gain advantage while they condemn poor and working-class rural whites as racist.

You hear the phrase “white privilege” nonstop in America these days, as the slogan has transcended the campus and entered popular culture.

Historically, the term apparently refers to the original European settlers who came to the United States and later equated the protections of the U.S. Constitution solely with their own majority ethnicity and race — a tribal and chauvinistic mindset that still governs politics and immigration the world over, from China and Japan to most African and South American countries.

Yet the singular transcendent logic of the Constitution and Declaration of Independence was that all people innately were created equal. It took over two centuries on the ground to catch up to such lofty idealism.

Yet given that immigration by the early 19th century was already bringing in millions of so-called non-white immigrants, in addition to Native and African Americans, America soon was at least evolving into a multiracial democratic nation united under one shared culture — a radical idea and the first such edgy experiment in human history.

During the civil-rights movement of the 1960s, the nation’s racial tensions were mostly still defined as a binary of a dominant white majority and an often discriminated-against African-American minority.

Years of past prejudice had sparked the idea of affirmative action, or federal reparatory programs accorded to a historically discriminated-against black minority.

Mueller Will Not Present ‘Collusion’ Evidence at Manafort’s Fraud Trial By Andrew C. McCarthy

https://www.nationalreview.com/2018/07/robert-mueller-paul-manafort-collusion-evidence-wont-be-used/

But that doesn’t mean he has no such evidence.

Paul Manafort faces two criminal trials, the first of which is scheduled to commence in the Eastern District of Virginia later this month. It is routine in such cases for the parties to file “motions in limine,” which ask the court to preclude evidence on topics that are claimed to be irrelevant to the charges and that could cause unfair prejudice or confusion.

The indictment on which Manafort will be tried primarily involves allegations of tax cheating and bank fraud. There are no charges involving so-called collusion in Russia’s interference in the 2016 presidential election, the suspected scheme that was the rationale for Robert Mueller’s appointment as special counsel. Manafort thus filed an in limine motion to keep the collusion issue out of the case. In responding, the special counsel agreed with the defense, representing that the prosecution “does not intend to present at trial evidence or argument concerning collusion with the Russian government.”

This has prompted some chirping from Trump supporters. They note that Manafort is accused in the Steele dossier of being the key cog in the supposed Trump–Russia “collusion” arrangement. The suggestion is that Mueller has no real collusion evidence despite the fact that the FBI has been investigating the matter for two years.

It may well be that Mueller does not have a prosecutable collusion case (indeed, we have long surmised as much). But that is not a conclusion that can sensibly be drawn from the unremarkable fact that the special counsel does not plan to prove collusion in the imminent Manafort trial. Because collusion evidence would not be germane to the fraud allegations that the jury will be asked to decide, there would be no reason to introduce such evidence, if it exists.

AMIL IMANI: IRAN IS RIPE FOR REGIME CHANGE

https://www.americanthinker.com/articles/2018/07/iran_is_ripe_for_regime_change.html

It is hard to believe that four decades has passed since the Islamic Revolution was forced upon the Iranian people and their freedom disappeared. Under the rule of these adherents of death, everything in Iran is deteriorating while Iran’s religious government is strong and has a great deal of control on everything. Too much control without independent checks and balances encourages corruption, nepotism and inefficiencies. As a result, the bulk of the nation’s wealth flows to a few select individuals.

This is a wake-up call for Iran’s authorities and the international community. Although denied by many through the past four decades, Iran is literally a political, social and economic time bomb closing in on a colossal detonation.

While Iran continues to develop its missile program that is sharply criticized by the United States and Israel, they simultaneously seek to suppress people’s desire to keep a share of the country’s wealth. Prosecution and imprisonment of innocent people and systematic and illegal abuse of detainees, along with hundreds of gruesome acts, have also been reported.

Iranians have witnessed several uprisings, but they have become numb and unable to function and conduct a normal life. The battle against the Islamic regime remains arduous and long. The mullahs will not give up power easily, even if that means the complete destruction of Iran.

Pressure To Break Up Facebook Builds The conservative-hating social media giant may soon get its comeuppance. Matthew Vadum

https://www.frontpagemag.com/fpm/270691/pressure-break-facebook-builds-matthew-vadum

America’s largest communications union, the 700,000-member Communications Workers of America (CWA), has joined an activist coalition called Freedom from Facebook that seeks to break up the monopolistic social media giant.

So far the groups supporting the Freedom From Facebook coalition are predominantly left-wing. Among them are MoveOn.org and Public Citizen. Facebook has about 2 billion users worldwide.

But the ideological makeup of the FFF coalition could change in a heartbeat if Facebook continues down its intolerant, authoritarian path. That’s because conservatives have long been abused by Facebook and this ill treatment has only intensified since the election of President Donald Trump. Conservatives are getting wise to being used and taken advantage of and they don’t like it.

The Left claims to have only the purest motives for wanting to take action against Facebook.

“We should all be deeply concerned by Facebook’s power over our lives and democracy,” said Brian Thorn of CWA, the newest member of the Freedom From Facebook coalition.

Facebook’s workers are not represented by CWA, but the union does represent more than 100,000 employees at AT&T Inc. Facebook’s contracted shuttle drivers and cafeteria workers reportedly belong to labor unions.

A Champion of Constitutional Safeguards Brett Kavanaugh has a fine record as a judge. Senate Democrats will give him their worst anyway. By David B. Rivkin Jr. and Andrew M. Grossman

https://www.wsj.com/articles/a-champion-of-constitutional-safeguards-1531189515

Days before President Trump announced his choice of Judge Brett Kavanaugh for the Supreme Court, Senate Democrats had vowed to oppose any nominee. Backed by an activist-fueled propaganda machine, they now will unleash relentless personal attacks—on Judge Kavanaugh’s Catholic faith, his “elitist” Yale degrees, his service in the George W. Bush administration.

As with the attacks last year on Justice Neil Gorsuch, they should be unavailing. Over Judge Kavanaugh’s 12 years on the U.S. Circuit Court of Appeals for the District of Columbia, he has developed an impressive record as a legal thinker and a champion of the Constitution’s structural safeguards against overweening government.

Typical is a 2008 dissent in which Judge Kavanaugh concluded that the Public Company Accounting Oversight Board was unconstitutionally structured because it improperly insulated the agency from political accountability. The opinion was a tour de force of historical exposition and originalist methodology—that is, interpreting the Constitution’s text as it was originally understood. The Supreme Court ultimately agreed, adopting the reasoning of Judge Kavanaugh’s dissent.

Yet he is equally wary of unbridled executive authority, as a 2013 case shows. When the Nuclear Regulatory Commission declined to proceed with licensing the proposed waste repository at Yucca Mountain, Nev., which the agency appeared to oppose on policy grounds, he wrote: “The President may not decline to follow a statutory mandate or prohibition simply because of policy objections.”

In articles and speeches as well as formal opinions, Judge Kavanaugh has been a leading critic of Chevron deference, the courts’ practice of giving agencies free rein to interpret their own statutory authority. In a 2016 law-review article, he wrote that Chevron encourages the executive branch “to be extremely aggressive in seeking to squeeze its policy goals into ill-fitting statutory authorizations and restraints,” cutting Congress out of the picture. “The American rule of law, as I see it, depends on neutral, impartial judges who say what the law is.”CONTINUE AT SITE

The UN Fraudulently Addresses “Extreme Poverty” in the United States by Francis Menton

https://www.gatestoneinstitute.org/12629/un-poverty-united-states

You may be aware that the UN actually has an official definition of “extreme poverty,” which is “liv[ing]… on less than $1.90 per person per day.” $1.90 per day would come to just under $700 per year.

An April 2018 study by John Early for the Cato Institute found that counting the $1.2 trillion of annual redistributions toward the income of the recipients — a sum often misleadingly excluded from poverty statistics — reduces the official poverty level in the U.S. from 12.7% all the way down to about 2%. And the remaining 2% would be people who for some reason had not sought out the benefits.

In other words, the U.S. distributes to its low-income residents resources beyond their income equal to an additional 40 times per person the amount officially deemed by the UN to constitute “extreme poverty.”

Is the United Nations a group of people of good faith, joining together in the effort to help bring peace and justice and economic development to the world? Or is it a group of haters of freedom and capitalism engaged primarily in spewing ignorance, malice or both toward the United States? For a clue, you might take a look at the “Report of the Special Rapporteur on extreme poverty and human rights on his mission to the United States of America,” recently issued by the UN’s so-called Human Rights Council.

Yes, this is the same Human Rights Council from which the U.S. just announced its withdrawal. It is also the same Human Rights Council that includes among its members China, Cuba, Pakistan, Saudi Arabia and Venezuela — with ambassadors who think that the best use of their time and resources is to criticize the economic and human rights record of the U.S.

Watching weather waves, missing climate tides By Viv Forbes

https://www.americanthinker.com/blog/2018/07/watching_weather_waves_missing_climate_tides.html

The climate alarm media, the bureaucracy, and the Green Energy industry follow an agenda served by inflating any short-term weather event into a climate calamity. They should take a long-term view.

Earth’s climate is never still – it is always changing, with long-term trends, medium-term reversals, and minor oscillations. Humanity is best served by those who use good science to study geology, astronomy, and climate history searching for clues to climate drivers and the underlying natural cycles and trends hidden in short-term weather fluctuations.

For the last 10,000 years Earth has basked in the Holocene Interglacial, which is the latest of many warm cycles within the Pleistocene Ice Age. There are small warm and cool cycles within the Holocene. Today we enjoy the Modern Warm Cycle (which started about calendar 1900), following the Little Ice Age, which bottomed in about 1750.

What does the future hold? The past gives clues to the future.

In every warm era, glaciers retreat, ice sheets melt, and sea levels rise. Coastal land, ports, and settlements are lost under the rising seas, but tundra, grasslands, and forests expand. Some corals manage to grow as fast as the seas rise, but others are drowned in deep water. The warmth drives more carbon dioxide from the seas, plants thrive, deserts shrink, and humans are well fed.

ELECTIONS ARE COMING: America Needs Leaders like Martha McSally By Elise Cooper

https://www.americanthinker.com/articles/2018/07/america_needs_leaders_like_martha_mcsally.html

“Drain the Swamp” is the rallying cry of Americans who want leaders, not politicians. This was the case for many World War II veterans who chose to serve their nation in a different capacity. It is no different today with Congresswoman Martha McSally (R-AZ), a representative of those veterans who care more about this country than their own political ambitions.

McSally has an impeccable resume. As a colonel in the Air Force she was part of the team that helped plan and execute U.S. air operations over Afghanistan shortly after 9/11. In January 1995, she became the first woman in U.S. history to fly a combat aircraft into enemy territory, in order to help enforce the United Nations’ “no-fly zone.” In July 2004, McSally took command of the 354th Fighter Squadron, becoming the first woman in U.S. history to command a combat aviation unit. A requirement that American military women wear veils while stationed in Saudi Arabia led her to stand up for American principles with a lawsuit in early 2002. This eventually led Congress to pass a bill ending the practice. She is now serving her second term after first being elected to Congress (R-AZ 8th district) in 2014. American Thinker had the privilege of interviewing her as she makes a run for Arizona’s open Senate seat.

Less than 1% of the total population serves in the military today. Yet, many post-9/11 veterans are stepping up to the plate to serve in Congress. McSally believes, “Being an elected official is a continuation of my service. Those who served in the military understand that our culture is not to walk away from a problem, but to do something about it. A lot of veterans are responding to this ‘call to duty.’ I am willing to work with those on the other side of the aisle, even the ones who I do not agree with. I think it is in a veteran’s DNA to be mission oriented, which means to see if there are any Venn Diagrams pieces that we can agree upon and work together.”