John Abeles M.D. Innate immune suppression by SARS-CoV-2 mRNA vaccinations The role of G-quadruplexes, exosomes, and MicroRNAs

Abstract

The mRNA SARS-CoV-2 vaccines were brought to market in response to the public health crises of Covid-19. The utilization of mRNA vaccines in the context of infectious disease has no precedent. The many alterations in the vaccine mRNA hide the mRNA from cellular defenses and promote a longer biological half-life and high production of spike protein. However, the immune response to the vaccine is very different from that to a SARS-CoV-2 infection. In this paper, we present evidence that vaccination induces a profound impairment in type I interferon signaling, which has diverse adverse consequences to human health. Immune cells that have taken up the vaccine nanoparticles release into circulation large numbers of exosomes containing spike protein along with critical microRNAs that induce a signaling response in recipient cells at distant sites. We also identify potential profound disturbances in regulatory control of protein synthesis and cancer surveillance. These disturbances potentially have a causal link to neurodegenerative disease, myocarditis, immune thrombocytopenia, Bell’s palsy, liver disease, impaired adaptive immunity, impaired DNA damage response and tumorigenesis. We show evidence from the VAERS database supporting our hypothesis. We believe a comprehensive risk/benefit assessment of the mRNA vaccines questions them as positive contributors to public health.

DeSantis’ COVID Vaccine Grand Jury Gets the Green Light From the Florida Supreme Court By Lincoln Brown

https://pjmedia.com/news-and-politics/lincolnbrown/2022/12/22/desantis-covid-vaccine-grand-jury-gets-the-green-light-from-the-florida-supreme-court-n1655816

On Thursday, the Florida Supreme Court gave the go-ahead to a request by Gov. Ron DeSantis to impanel a statewide grand jury to investigate potential wrongdoings related to COVID-19 vaccines.

The Tampa Bay Times reported that Hillsborough County Circuit Judge Ronald Ficarrotta will preside, with members to be selected from five judicial districts. DeSantis made the initial request on the 13th of this month, stating at the time that “there are good and sufficient reasons to deem it to be in the public interest to impanel a statewide grand jury to investigate criminal or wrongful activity in Florida relating to the development, promotion, and distribution of vaccines purported to prevent COVID-19 infection, symptoms, and transmission.”

DeSantis was a one-time proponent of the vaccines for certain demographics, namely senior citizens. However, he became skeptical of them over time, in particular because of the claims about their efficacy. The Associated Press reported that DeSantis contends that drug manufacturers had a financial interest in creating a mindset that vaccinated people could not transmit the virus to another person. According to the article in the Times, the scope of the grand jury will include:

…people and ‘entities, including, but not limited to, pharmaceutical manufacturers (and their executive officers) and other medical associations or organizations involved in the design, development, clinical testing or investigation, manufacture, marketing, representation, advertising, promotion, labeling, distribution, formulation, packing, sale, purchase, donation, dispensing, prescribing, administration, or use of vaccines purported to prevent COVID-19 infection, symptoms, and transmission.’

The Subsidy Tango of Bill Gates and Joe Manchin The West Virginia Senator and the billionaire investor score a windfall in the Inflation Reduction Act.

https://www.wsj.com/articles/the-subsidy-tango-of-bill-gates-and-joe-manchin-terrapower-climate-spending-john-barrasso-jennifer-granholm-11671741449?mod=opinion_lead_pos1

Bill Gates sold West Virginia Sen. Joe Manchin on this year’s Democratic climate spending blowout as a way to put unemployed coal workers to work building advanced nuclear reactors. Now we learn, belatedly, that these projects depend on Russia for fuel and will cost taxpayers more than advertised.

The Energy Department last year awarded up to $2 billion for an advanced nuclear reactor “demonstration” project in Wyoming being developed by TerraPower, a company Mr. Gates founded. These advanced reactors have been promoted because they take up significantly less space than conventional reactors and could theoretically use reprocessed nuclear fuel.

TerraPower’s reactors will also supposedly be able to ramp up and down to balance intermittent solar and wind power on the grid. But the technology currently requires enormous government subsidies to be commercially viable. Reactors also require many more years to build than renewable and fossil-fuel plants owing to stricter licensing requirements and environmental reviews.

TerraPower planned to complete the Wyoming generator by 2028 assuming no hang-ups. There always are. So it wasn’t surprising when TerraPower disclosed this month that completion will be delayed by at least two years. But the reason was alarming: TerraPower was counting on Russia to supply it with high-assay, low-enriched uranium (HALEU) fuel.

Biden Screamed and Dropped F-Bombs As Border Crisis Ravaged Sarah Arnold  

https://townhall.com/tipsheet/saraharnold/2022/12/22/biden-screamed-and-dropped-f-bomb-as-border-crisis-ravaged-n2617493

The southern border is in shambles. It has been overrun by illegal migrants and drug cartels who are bringing dangerous substances and people into the U.S., yet America’s president believes that there are “more important” things to worry about. 

However, it turns out that President Joe Biden was and is fully aware of the havoc he has caused on the border. 

According to a new book titled, “The Fight of His Life: Inside Joe Biden’s White House,” author Chris Whipple said that Biden screamed and cursed as the crisis at the border escalated. 

Whipple, who spent the first two years shadowing the Biden Administration, recalled the moment the president learned that thousands of illegal migrants were storming the southern border. 

“Meanwhile, illegal immigrants kept arriving. And Biden was furious,” Whipple wrote, adding “aides had rarely seen him so angry. From all over the West Wing, you could hear the president cursing, dropping f-bombs.” 

Despite Biden never visiting the border or addressing the problem at all, he reportedly had a “short fuse” when it came to the matter. 

“Next to vaccine disinformation, this was the thing that made Biden’s blood boil,” the book reads. 

A senior official reportedly told Whipple that Biden was frustrated with the “lack of solutions” his team brought to him as the country began to become more aware of the problem. 

The Marine Corps Goes Woke Sarah Arnold  

https://townhall.com/tipsheet/saraharnold/2022/12/22/marine-corps-goes-woke-n2617456

In a world where everything that was once normal is now woke, it’s no surprise that the Marine Corps has also turned the tide. 

A newly released academic report from the University of Pittsburgh recommended that the U.S. Marine Corps drop the words “sir” and “ma’am” used to address senior officers to avoid “misgendering” drill instructors despite there only being 14,000 females in the Marine Corps, which makes up of only 7 percent of the branch.

Instead of using the words “sir” and “ma’am,” recruits in the military services refer to their drill instructors using their ranks or roles followed by their last names. 

The 738-page report highlights a $2 million study that was conducted to examine gender-integrated recruit training, which claimed that the change would make both genders feel more comfortable when being addressed by peers. 

However, not everyone is on board with the woke change. 

According to the Marine Corps Times, Col. Howard Hall, chief of staff for Marine Corps Training and Education Command, expressed several concerns. 

“That’s going to take some effort,” Hall said, adding “honestly, that’s not a quick fix. What is inculcating in our young recruits that will or will not be reinforced when they graduate and enter the fleet Marine force? So again, we want to avoid any quick-fix solutions that introduce perturbations down the line.”

Saudi Arabia Welcomes China’s Xi as US Snubs Allies, Courts Enemies by Lawrence A. Franklin

https://www.gatestoneinstitute.org/19251/saudi-arabia-welcomes-china

China is fully exploiting the cooling of US-Saudi relations engineered by the Biden administration’s repeated public personal attacks on Saudi Crown Prince Mohammed bin Salman (MBS) as well as perceived decreased support for the Saudi-led coalition’s efforts to blunt Iranian expansionism in Yemen.

The Saudis had most likely hoped that the US would finally scuttle the Iran nuclear deal for good, which did not take place.

Just a few weeks into the Biden administration, on February 12, 2021, Secretary of State Antony Blinken removed the Houthis from the list of Foreign Terrorist Organizations. A few months later, the Houthis expressed their appreciation by raining rockets and missiles down on Saudi Arabia’s “critical energy facilities” and the United Arab Emirates.

Saudi leaders therefore seem to be seeking to diversify their commercial and security links by improving relations with China, as superficially symbolized by the pomp and ceremony associated with Xi’s welcome to Riyadh. If so, this Saudi initiative plays well with Xi’s concept of an emerging multi-polar world.

Xi has agreed to buy more oil from Gulf Cooperation Council states but suggested that the purchases be paid for in Chinese yuan rather than US dollars. If the oil-exporting states agree to Xi’s request, it will further reinforce the notion that US influence with Saudi Arabia is on the decline.

As evidence of this negative trend in US prestige, the Saudi crown prince ignored US warnings not to sign deals with the Chinese telecommunications company Huawei. Saudi Arabia inked Huawei-associated contracts on data centers and cloud computing.

The Saudis seem to be welcoming China as a potential strategic partner — one that will not, unlike the US, interfere in what the Kingdom undoubtedly considers its most urgent existential need.

China is fully exploiting the cooling of US-Saudi relations engineered by the Biden administration’s repeated public personal attacks on Saudi Crown Prince Mohammed bin Salman (MBS) as well as perceived decreased support for the Saudi-led coalition’s efforts to blunt Iranian expansionism in Yemen.

Sanctuary Idealism Crashes into Reality Politicians who benefited from sanctuary advocacy now admit the obvious truth: Sanctuary policies are unsustainable. By Brian Lonergan

https://amgreatness.com/2022/12/21/sanctuary-idealism-crashes-into-reality/

The late, great Rush Limbaugh frequently opined on his radio show that progressivism’s appeal stems from the fact that its followers are required to do nothing but “care.” Simply vent empathy or outrage—especially on social media—on behalf of an approved left-wing cause, and your otherwise dreary life can seem meaningful in the belief you are both morally superior to your ideological opponents and also saving the world. It’s a seductive pitch that has been all too successful.

The political benefits of this ideology have not been lost on state and local elected leaders, many of whom are true believers anyway. They enthusiastically virtue signal on behalf of numerous issues, and one of their favorites is sanctuary policies as a purported act of mercy toward illegal aliens. For years this was populism on easy mode, as politicians basked in the approval from their activist base without having to do much hard work.

Thanks to a combination of the Biden Administration’s disastrous border policies and fed-up red state governors, however, the party is over as sanctuary rhetoric is crashing into reality, and the curtain is being pulled back to expose their folly.

Evidence of this phenomenon can be seen even in the words of immigration realpolitik coming from the most unlikely places. In California, a hotbed of irrational sanctuary policies, Governor Gavin Newsom recently toured the southern border of his state and warned of dire consequences should the White House succeed in its effort to end Title 42 border enforcement.

“The fact is, what we’ve got right now is not working and is about to break in a post-42 world unless we take some responsibility and ownership,” Newsom said.

Responsibility? Ownership? These are uncharted waters for Newsom. He has spent most of his governorship pandering to noncitizens with initiatives like universal healthcare and state IDs for illegal aliens. For someone like Newsom to be warning that the end is near is a sign that we may be approaching a point of no return with Biden’s border sabotage.

Big-city mayors, in particular, have benefited from being sanctuary advocates. They’re now admitting the obvious truth that sanctuary policies are unsustainable. Since Governors Greg Abbott of Texas, Ron DeSantis of Florida, and Doug Ducey of Arizona began sending busloads of migrants to New York City, Mayor Eric Adams has been forced to walk a tightrope of defending sanctuary policies while acknowledging his city is struggling to accept the new arrivals.

Are Universities Doomed? Elite university degrees certify very little. And the secret is out.  By Victor Davis Hanson

https://amgreatness.com/2022/12/21/are-universities-doomed/

In a famous exchange in the The Sun Also Rises, Ernest Hemingway wrote: “How did you go bankrupt?” Bill asked. “Two ways,” Mike said. “Gradually, then suddenly.”

“Gradually” and “suddenly” applies to higher education’s implosion. 

During the 1990s “culture wars” universities were warned that their chronic tuition hikes above the rate of inflation were unsustainable. 

Their growing manipulation of blanket federal student loan guarantees, and part-time faculty and graduate teaching assistants always was suicidal. 

Left-wing indoctrination, administrative bloat, obsessions with racial preferences, arcane, jargon-filled research, and campus-wide intolerance of diverse thought short-changed students, further alienated the public—and often enraged alumni.

Over the last 30 years, enrollments in the humanities and history crashed. So did tenure-track faculty positions. Some $1.7 trillion in federally backed student loans have only greenlighted inflated tuition—and masked the contagion of political indoctrination and watered-down courses. 

 But “gradually” imploding has now become “suddenly.” Zoom courses, a declining pool of students, and soaring costs all prompt the public to question the college experience altogether. 

Nationwide undergraduate enrollment has dropped by more than 650,000 students in a single year—or over 4 percent alone from spring 2021 to 2022, and some 14 percent in the last decade. Yet the U.S. population still increases by about 2 million people a year.

Men account for about 71 percent of the current shortfall of students. Women number almost 60 percent of all college students—an all-time high. 

Monotonous professors hector students about “toxic masculinity,” as “gender” studies proliferate. If the plan was to drive males off campus, universities have succeeded beyond their wildest expectations. 

Must-see video: Tucker Carlson takes on the Zelenskyy money grab By Andrea Widburg

https://www.americanthinker.com/blog/2022/12/mustsee_video_tucker_carlson_takes_on_the_zelenskyy_money_grab.html

Last night, Ukrainian President Volodymyr Zelenskyy showed up in Congress to demand money. As one, the entire body of American politicians swooned before the man. One person who did not swoon was Fox pundit Tucker Carlson, who pointed out some uncomfortable truths and asked the all-important question about our politicians joyously pushing us towards a hot war with a nuclear Russia. Who benefits?

Russia may be nuclear, and it may have a very nasty, cruel man at its head, but it’s important to note that Russia, despite its natural resources, is a nothing of a country. Unlike the former Soviet Union, which had tentacles, satellites, colonies, and interests around the globe, not to mention all sorts of unwilling neighboring countries swept into its net to make up that Union of Soviet Socialist Republics, Russia is a smaller country with no serious interests abroad.

Yes, Putin meddles in Syria and Turkey, but he’s no Xi Jinping. Other than natural gas, which Europe needs, Russia has not coopted all of America’s manufacturing, from our clothes to our appliances to our medicines. Mostly, Russia does not affect us.

Indeed, there’s only one reason Russia is perceived as a threat, and that’s because leftists have come to believe their own Russia hoax accusation that Putin put Trump in the White House. He didn’t but, because Democrats and NeverTrumpers (i.e., the Republican establishment that hates Trump as much as the Democrats do) believe that, Putin must be destroyed.

What none of these fanatics have thought through is what happens if they are able to get rid of Putin. Who comes next? Xi? A megalomaniac with dreams that go beyond Russia’s current borders? Biden, who needs help putting on his pants in the morning so that the zipper faces forward, has no answers.

The insistence that Ukraine is a beleaguered democracy is nonsense, too. Ukraine is and has long been an utterly corrupt country to which Western politicians go to launder taxpayer money.

Thanks to Elon, the FBI has a lot to answer for By Michael Letts

https://www.americanthinker.com/blog/2022/12/thanks_to_elon_the_fbi_has_a_lot_to_answer_for_.html

Things have not been good for the Federal Bureau of Investigation this year.

Thanks to its new owner Elon Musk, the “Twitter Files” have been making the rounds, revealing just what kind of relationship the social media giant has with the bureau. Apparently the two had “constant and pervasive” communications, with the FBI treating Twitter as a “subsidiary.” In other words, they were making note of accounts and tweets that needed to be taken action against.

That aligns with reports about surveillance on citizens and infringing on free speech rights in a number of ways — all in the name of “justice.”

Republicans are working on getting hold of these “Twitter Files,” in hopes of being able to get several subpoenas against both the FBI and the Department of Justice. Leading this charge is Rep. Mike Turner (R-Ohio), who will soon be the chairman for the House Intelligence Committee.

Speaking with Fox News on a recent episode of Sunday Morning Futures, he stated, “We are definitely pursuing the Department of Justice and also the FBI. We certainly intend to pursue subpoena power to expose the extent to which the FBI has been doing this.”

“While we pursue intelligence community to try to hold them accountable, while we’re doing that, Elon Musk is showing what’s happening on the other side with the willing partners, the mainstream media, social media, and really exposing coordination that was occurring between the FBI and them,” he continued.

And how. With Republicans set to take back the House next month, it appears they can finally get things moving as far as taking a closer look at what the FBI is really doing.

Turner believes that, by attaining these files, “we can cut off the funding and prevent, obviously, average Americans being impacted by FBI actions.”

But this goes much deeper than that. “The FBI… under the cover of saying they were pursuing foreign malign influence, had really exploded into activities that involved engaging with mainstream media and social media, and really impacting what is the normal debate of democracy. What’s really troubling here in my opinion is this is not based on intelligence.”