https://bariweiss.substack.com/p/he-was-a-world-renowned-cancer-researcher?s=r
In 2018, David Sabatini was a world-renowned molecular biologist. He was a tenured professor at MIT. He ran a major lab at the Whitehead Institute, overseeing a team of 39 researchers, postdocs and technicians. Their job was to disentangle the mystery of the mTOR signaling pathway, a protein Sabatini had discovered while still in medical school, at Johns Hopkins. The mTOR signaling pathway plays a critical role in tumor development. Figuring out how it works would go a long way toward saving countless lives.
This was why Sabatini was predicted to win the Nobel Prize. It was how he reeled in between three and four million dollars every year for his lab from the National Institutes of Health, the Pentagon and the Howard Hughes Medical Institute, among others. It is why his colleagues have described him to me with words like “genius,” “one of the best scientists alive,” and “a pillar.”
“It’s like working for Steve Jobs. He can be brutal,” said one scientist. “But why would you want to work for anyone else?”
Today, Sabatini is unemployed and unemployable. No one wants to be associated with him. Those who do risk losing their jobs, publishing opportunities, friends, visas, and huge federal grants. “What wormhole did my life take, to billionaires and protests and being called a sexual predator? What quirk in the universe allowed this to happen?” Sabatini asked me.
The entrance to the wormhole can be found in Rockville, Maryland, at a hotel that Sabatini was staying at while attending a conference about lysosomes and cancer sponsored by the National Institutes of Health. There, on the night of April 18, 2018, after an evening of whiskey tasting—Sabatini is a whiskey aficionado—he and Kristin Knouse had sex. Knouse was an incoming cancer researcher at the Whitehead, where she would also head her own lab; hers focused on liver regeneration. He was 50. She was 29. He had split with his wife, and was in the process of getting a divorce.
