http://israel21c.org/health/new-solution-kills-hospital-superbugs
New ‘solution’ kills hospital superbugs By Karin Kloosterman
Resistant bacteria are soon to meet their match: a genetically engineered fluid that restores their susceptibility to antibiotics.
Every patient, nurse, doctor and visitor to a hospital knows the drill: hands get a splash of antibacterial fluid found at every bedside, entrance and exit. Keeping hands clean can prevent some infections, but superbugs — those sometimes deadly bacterial strains resistant to antibiotics — can outwit the best hygiene practices.
Hospital-acquired infections are one of the leading causes of preventable death in the developed world today, with 100,000 people in the United States alone dying every year from bugs they catch as patients in the hospital, according to the World Health Organization. The old and very young are at an especially high risk of infection from resistant bacteria that can spread like wildfire.
But now superbugs may have met their match, thanks to a genetically engineered cleaning solution developed in Israeli laboratories.
Costing only a few dollars a quart, the solution is non-toxic to patients and can be spread on hospital surfaces to kill what conventional soaps and antibiotics can’t, report researchers Rotem Edgar from the Tel Aviv Sourasky (Ichilov) Medical Center and Udi Qimron from Tel Aviv University. They detailed their technology recently in the journal Applied and Environmental Microbiology.
Weakening the superbugs
The solution uses a laboratory-grown virus called a bacteriophage, which disrupts the DNA of resistant bacteria and renders them susceptible to antibiotics.
“We have genetically engineered the bacteriophages so that once they infect the bacteria, they transfer a dominant gene that confers renewed sensitivity to certain antibiotics,” says Qimron, who believes his solution will one day be part of every hospital’s anti-germ arsenal.
The researchers say that the new spray could be applied on any surface where there is a high concentration of germs, such as door handles, faucets, bedrails and handrails.
The product is now ready to be tested, first on a nasty strain of E. coli that leads to urinary trac