RUTHFULLY YOURS

1. In December, 2016, Israel is unprecedentedly integrated into the global economy, highlighting the successful battle against BDS (boycott, divestment and sanctions), while rejecting pessimism and fatalism.

2. According to a Bloomberg study: “An examination of foreign capital flow into Israel shows a near tripling from 2005 when the so-called BDS was started…. Israel’s economy is expected to grow 2.8% in 2016, compared with 1.8% for the US and the EU. In 2015, Israel’s industrial high-tech exports rose 13%, from 2014, to $23.7BN….”

3. 2016 is already a record year for total (mostly foreign) investments in Israel’s young high tech companies, exceeding the $4.4BN invested in 2015. For instance, Israel’s NeuroDerm, which develops drugs for central nervous system diseases, is expected to raise $75MN, on NASDAQ, by December 12, 2016. Some of the recent investments were made by the US-based Johnson & Johnson’s Development Corporation, the Australian Stock Exchange, the German medical equipment giant B. Braun Melsungen AG, China’s Internet giant Alibaba and Japan’s Sun Corporation.

4. A trilateral cooperation agreement has been concluded between Israel’s Mobileye – a collision avoidance sensor developer – Delphi Automotive, the UK-based global automotive parts manufacturer and the Silicon Valley-based Intel, aiming to manufacture a self-driving car by 2019. A similar partnership was struck between Mobileye, Intel and the German car giant, BMW.

5. A wave of acquisitions of Israeli companies by global giants persists, as evidenced by the November, 2016 acquisition of Israel’s valve repair device company, Valtech Cardio Ltd., by the Irvine, California-based Edwards Lifesciences Corp., for $340MN in stock and cash, in addition to $350MN in milestone payments over ten years and $300MN for Valtech’s research and development program. Just like 200-250 other (mostly US) major global hightech companies, Edwards has leveraged Israel’s brain-power by operating a research and development center in Israel, since the 2004 acquisition of Israel’s PVT for $90MN and milestone payments.

6. The London-based mega-billion-dollar Chinese/European XIO Group has acquired Israel’s Meitav-Dash Investment House for $400MN. In 2015, XIO acquired Israel’s medical device company, Lumenis, for $510MN. China’s telecommunications giant, Xinwei, is negotiating the acquisition of Israel’s Spacecom Satellite Communications for $190MN, reflecting the surging Chinese interest in the Israeli market and the significantly expanding Israel-China trade balance from $50MN in 1990 to $11BN in 2015, in addition to $15BN in acquisition of Israeli companies. The Hong Kong-based Rightleder Holding Group aims to acquire Israel’s sewage recycling (water purification) company, Advanced Membrane Separation. Also two Chinese capital funds, CDH and ZZ explore the acquisition of ironSource, Israel’s largest Internet company, for $1BN.

7. The Israel-India trade balance surged from $200MN in 1992 – when diplomatic relations were normalized – to $3BN in 2009 and $5BN in 2015, accompanied by a rise in two-way-tourism, paving the road to a negotiated free-trade-agreement, and highlighting India as one of Israel’s fastest growing trade partners in the commercial and defense areas. New Delhi has become the top customer for Israel’s defense industries, in addition to a series of co-development and co-production initiatives with Israel – in the face of joint economic and national security challenges – while Israel has become the number two/three exporter of military systems to India, following Russia and the USA.

8. On November 16, 2016, India signed $1.4BN contracts with the Israel Aerospace Industries (IAI), purchasing two additional Phalcon/IL-76 Airborne Early Warning and Control Systems and ten Heron unmanned aerial vehicles. IAI has submitted a proposal for the co-development, in India, of an advanced version of the Heron. The growing Israel-India defense ties are demonstrated by the recent Indian procurement of Rafael’s Gil anti-tank missiles, upgrades of Indian tanks by Elbit Systems and a joint development of the Barak-8 surface-to-air missile.

ISRAEL’S MEDICAL ACHIEVEMENTS

Key enzyme discovery in fight against cancer. Israel Technion researchers have found that the ubiquitin enzyme RNF4 binds to oncogenic proteins to give cancer cells longer lives. Increased levels of RNF4 have been found in colon and breast cancer patients. Removing or inhibiting RNF4 leads to the death of cancer cells.
http://www.technion.ac.il/en/2016/12/crucial-enzyme-for-tumor-development/
https://www.youtube.com/watch?v=yC53-lREHQg

Success in Sickle-Cell Disease trial. Israeli biotech Gamida Cell published positive results in its Phase I/II trial of NiCord, for the treatment of Sickle-Cell Disease (SCD). All the patients that completed the trial were free of SCD symptoms.
http://www.globes.co.il/en/article-gamida-reports-positive-nicord-results-1001165382

Full remission in Leukemia treatment trial. Israel’s BioSight has reported that in treating patients with its Astarabine leukemia treatment, three patients with late-stage leukemia achieved full remission to date. Good results were also reported for older patients over 80.
http://www.globes.co.il/en/article-biosight-completes-successful-cancer-drug-trial-1001165482

Sleep disorder treatment for autistic kids. Israeli biotech Neurim (featured Nov 20) has signed marketing agreements for its new Rx PedPRM treatment for sleep disorders in children with autism spectrum disorders and neurogenetic diseases. Kuhnil will market Rx PedPRM in Korea; Aspen in Australia and New Zealand.
http://www.neurim.com/news/2016-12-06/neurim-pharmaceuticals-paediatric-prolonged-release-melatonin-pedprm-to-be-marketed-by-kuhnil-pharmaceutical-in-south-korea/

Portable blood test for malaria. (TY Atid-EDI) Israel’s Sight Diagnostics (SightDx) (see here) in collaboration with the US Army Medical Research Directorate Kenya (USAMRD-K) is developing a portable malaria and complete blood count (CBC) reader. It will be calibrated and tested in clinical trials at the USAMRD-K Field Station in Kisumu, Kenya. http://www.prnewswire.com/news-releases/sight-diagnostics-ltd-and-the-united-states-army-announce-a-joint-collaboration-598337901.html

14 more hearts mended in Tanzania. Israeli surgeons from Save a Child’s Heart were back (again) in Tanzania, fixing another fourteen young, faulty hearts. The Israelis worked with a German team from Berlin’s Deutsches Herzzentrum during the five-day medical mission.
http://www.israel21c.org/israeli-german-medical-team-gives-14-children-gift-of-life/

Device to keep track of insulin doses. Israel’s Insulog is a device to help diabetes patients keep track of their insulin doses and prevent accidental overdoses. It snaps onto most types of disposable insulin pen, monitors and logs the dose and sends data to a smartphone app. It displays details of the last dose to the user.
Insulog is funding on Indiegogo. https://www.youtube.com/watch?v=0vscMWDcjlA
http://www.timesofisrael.com/israel-smart-tracker-aims-to-keep-tabs-on-insulin-shots/
https://www.indiegogo.com/projects/insulog-the-smart-snap-on-insulin-tracker-health–2#/

Israeli startup Insulog, which has created a device that helps diabetes patients keep track of their insulin doses, on Wednesday started a campaign to raise $50,000 via the crowdfunding platform Indiegogo.

The funds, said CEO and founder of the Ramat Gan-based firm Menash Michael, will help the company get the necessary US Food and Drug Administration and European permits to market the product. Contributors to the campaign will be able to get the product for $119, delivery of which will take place in summer 2017 when the approvals are in place, he said.

Diabetes patients who use an insulin pen to inject the hormone must remember to take the right dose at the right time, to help maintain stable sugar levels in the blood and to avoid over- or under-dosing, which could lead to life-threatening situations.

Even the most conscientious of patients can have a tough time managing the condition: they need to remember what they ate along with when they took their last dose of insulin and how many units they injected.

Indeed, Michael, who has suffered from Type 1 diabetes for over 30 years, ended up in the emergency room after he accidentally over-injected himself with insulin. After that experience, he came up with the idea for the smart, connected insulin tracker, the Insulog, to help diabetic patients like himself keep track of their medication regimen.

Smart sensors

The device, which snaps on to most types of disposable insulin pens, is equipped with smart sensors follow the pen vibrations and that reset each time a new dose of insulin is administered. An algorithm analyzes the clicks of the insulin pen, record the amounts taken and sends the information to a smartphone app. The pairing with the app enables users to view their entire injection history and share the information with their physician.

When the Insulog device is turned on for reuse, it displays data from the user’s most recent dose, showing when the last injection was administered and the quantity taken.

After his overdose, “now, I am hyper-alert of my insulin intake, and Insulog helps me to never make that mistake again,” said Michael, who founded the company in 2014. “There are hundreds of millions of people in the world who could greatly benefit” from the device, he said.

One of the most interesting stories, if not the most puzzling, is the close understanding and amity between Jerusalem and Moscow. While the Russian Air Force pounds the civilian population in Aleppo on behalf of the Syrian dictator Bashar Assad and his Iranian allies, Russia is coordinating the moves of its Air Force in Syria with Israel’s Air Force. Moscow is not interfering with Israeli attacks on Hezbollah convoys carrying lethal arms shipped to Syria by Iran, as the Shiite terrorist group is attempting to move these arms to Lebanon. Walla, a Hebrew language Israeli news outlet wrote on December 1, 2016 that “Russia’s silence following reports that the Israeli Air Force bombed an arms depot and a Hezbollah bound weapons convoy in Syria on Wednesday might signal ‘tacit consent’ to such action as long as they do not harm Kremlin’s interests.” Israel, on its part, is staying out of the civil war in Syria, but provides medical assistance to wounded opposition fighters combatting the Assad regime.

The Obama administration failure to act on its announced “Red Line,” (on Assad’s use of chemical warfare on fellow Syrians) and subsequently leaving the Syrian arena in Russian hands, has damaged U.S. credibility in the region. It has also encouraged Russia to take aggressive action against opposition forces supported by the U.S., and Syrian civilians.

Gen. Igor Konashenkov, spokesman for the Russian defense ministry said according to Russian RT-TV (11/29/2016) that, “Over the past few days, well planned and careful action by the Syrian troops resulted in a radical breakthrough. Half of the territory previously held by the militants in eastern Aleppo has been de facto liberated.” Konashenkov’s cynical statement referring to the Assad regime’s brutal actions in attacking (along with Russian aerial support) civilians in homes, hospitals and schools with barrel-bombs to be “well planned and careful action,” sharply contrasts with Israeli hospitals opening their doors to perform truly humanitarian work by treating wounded Syrian civilians and fighters.

Konashenkov also stressed that “over 80,000 Syrians, including tens of thousands of children, have been freed. Many of them, at long last were able to get water, food and medical assistance at humanitarian centers deployed by Russia. Those Syrians served as human shields in Aleppo for terrorists of all flavors.” That statement is turning the truth upside down. After relentless bombing by Russian and Syrian jets that have killed thousands (mostly Sunni civilians), these Syrians do not consider Russia’s role as “humanitarian.”

Putin’s Russia has saved Bashar Assad’s skin, and has done so for purely Russian interests, including air and naval bases in the Latakia Governorate of northwestern Syria, bordering the coveted Mediterranean Sea. Putin’s Russia has planned to sell, and according to Russian and Iranian sources, already delivered to Iran the highly sophisticated S-300 air defense system. Israel’s Prime Minister Benjamin Netanyahu, in his many meetings with Russia’s President, Vladimir Putin, implored the latter not to sell such weapons to the Islamic Republic of Iran. Thomas Shannon, U.S. Under-Secretary of State for Political Affairs, said that, “We have made it very clear to the Russians that we consider this (the sale of the S-300) to be a bad move, that we consider it to be destabilizing and not in keeping with what we’ve been trying to accomplish, not only through the JCPOA (Joint Comprehensive Plan of Action, commonly known as the Iran nuclear deal) , but broadly in terms of our engagement with Iran.”

TEL AVIV—Emboldened by the election of Donald Trump in the U.S., some Israeli lawmakers and Jewish settlers are pushing the contentious notion of annexing parts of the West Bank, which could threaten the long-stated goal of establishing a separate Palestinian state.

Since the Oslo Accords of the 1990s, the U.S., Israel and Palestinians have sought the establishment of a Palestinian state in the rough boundaries of the West Bank and Gaza Strip. A move to even partially annex the West Bank and impose Israeli law would depart from longstanding U.S. policy toward Israel, and would likely spark condemnation in Europe and parts of the Middle East.

But some of Mr. Trump’s campaign advisers have argued that the U.S. shouldn’t force a so-called two-state solution on the parties. The potential for a major shift in U.S. policy by the incoming Trump administration has stirred hopes of annexation among Jewish settlers.

“It’s easily doable,” said Eliana Passentin, 42, who lives in the settlement of Eli in the central West Bank. “I see it happening soon.”

The U.S. election has also changed the way Israeli officials discuss the status of the West Bank publicly.

“We can’t reach a Palestinian state. I oppose it, others favor it. But we all agree that it’s not going to happen tomorrow,” Naftali Bennett, the conservative leader of the Jewish Home party and a member of Prime Minister Benjamin Netanyahu’s ruling coalition, said last month at a conference in Jerusalem after the election.

Mr. Bennett advocates giving Palestinians in West Bank cities limited autonomy and imposing Israeli law in parts of the territory, while boosting spending on infrastructure to improve the quality of life for Palestinians and Jewish settlers alike.

On Monday, the Israeli parliament, known as the Knesset, have preliminary approval to legislation proposed by Mr. Bennett’s party that would legitimize thousands of Jewish settler homes in the West Bank that are illegal under current Israeli law. The legislation still faces further votes in the Knesset.

Officials with the Palestinian Authority, which governs cities in the West Bank, condemn talk of Israeli annexation. The Gaza Strip is governed separately by the Islamist movement Hamas.

At the same time, a Trump administration could bring fresh perspective to the conflict, according to Shukri Bishara, minister of finance in the Palestinian Authority. “This conflict requires creative thinking,” he said.

The Palestinians plan to put forward a United Nations Security Council resolution before the end of the year that would label settlements illegal, officials said. They hope that the U.S., which has consistently vetoed resolutions Israel objects to, won’t oppose such a move.

In Istanbul, where a majority of Turkey’s 17,000 Jews live, unknown people recently started hanging posters in a posh district. The posters call on Muslims “not to be fooled by the missionary activities of Jew-servant Jehovah’s Witnesses.” They say: “These people are trying to destroy the religion of Islam.” Signed: Sons of Ottomans.

Erdogan’s ideological hostility to the Jewish state and his ideological love affair with Hamas have not disappeared.

Erdogan thinks that Israel’s military action in response to Hamas’s rockets indiscriminately targeting Israeli citizens is no different than the murder of six million Jews by a lunatic. “There is no point in comparing and asking who is more barbaric,” Erdogan concluded. In other words, Erdogan thinks that Hitler and the Israel Defense Forces are “equally barbaric.”

Yes, blessed are the peacemakers. Nevertheless, the Turkish-Israeli “peace” may not be easy to sustain.

Modern Turkey has never been so disconnected from its Western allies. Its Islamist president, Recep Tayyip Erdogan, recently accused the West of helping the Islamic State of Iraq and Syria (ISIS). His evidence? Because, he said, ISIS is fighting with Western weapons — overlooking, of course, that they were probably captured or stolen.

This dislike and hostility is not unrequited. On November 24, the European Parliament voted overwhelmingly for a motion calling to suspend Turkey’s membership talks with the European Union (EU), citing “disproportionate, repressive measures” taken by Erdogan’s government. The motion, although non-binding, passed 479 to 37 in favor. In retaliation, Erdogan threatened that “if the EU goes further,” Turkey will open its border gates and let refugees stream toward Europe.

The Turks, too, are distancing themselves from the idea of EU membership. According to a survey by the pollsters ANDY-AR, 75.3% of Turks believe that their country is drifting away from accession, while only 19.9% believe it is not. Forty-four percent think freezing membership talks would be a positive development.

Confirming the growing anti-Western mood, Erdogan’s spokesman, Ibrahim Kalin, wrote in a newspaper column: “With its internal problems, micro-nationalisms and the Brexit process, Europe is narrowing down its strategic outlook and losing its relevance.”

Against this backdrop, Turkey is normalizing its relations with Israel — in theory, at least. Ankara and Jerusalem agreed to appoint ambassadors to each other’s country after an absence of more than six years. Two prominent career diplomats, Kemal Okem and Eitan Na’eh, will struggle to improve ties in Tel Aviv and Ankara, respectively. They will have a hard job. The diplomats may be willing, but with Erdogan’s persistent Islamist ideological pursuits, they would seem to have only a slim chance of succeeding.

Turkey’s dwindling Jewish community is uneasy over increasing signs of anti-Semitism in an increasingly Islamized country. In Istanbul, where a majority of Turkey’s 17,000 Jews live, unknown people recently started hanging posters in a posh district. The posters call on Muslims “not to be fooled by the missionary activities of Jew-servant Jehovah’s Witnesses.” They say: “These people are trying to destroy the religion of Islam.” Signed: Sons of Ottomans.

Feeling unsafe, more than 2,500 Turkish Jews have recently applied for Spanish citizenship, and hundreds applied for Portuguese citizenship. Only last year, 250 Turkish Jews emigrated to Israel. That being the case, Islamist Turks are warning their fellow Muslims against missionary activities of Jehovah’s Witnesses who are, according to them, “servants of Jews.”