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MEDICINE AND HEALTH

Paul T. Williams Equity Over Accuracy in Kidney Care A new formula moves blacks to the front of the line for treatment, regardless of need.

https://media5.manhattan-institute.org/iiif/2/wp-content%2Fuploads%2Fsites%2F5%2FEquity-Over-Accuracy-in-Kidney-Care.jpg/full/!99999,960/0/default.jpg

“Health equity” could be claiming new victims. More than 10 million nonblack Americans with chronic kidney disease may have seen their treatments or transplants delayed because of policy changes enacted after 2020’s “racial reckoning.” Some of those patients now face greater risk of death because national transplant organizations have embraced racial activism.

The United Network for Organ Sharing (UNOS), a quasi-governmental nonprofit that runs American transplant centers, enacted a significant policy change. The network compiles the national waitlist for kidney transplants and consults a formula that helps determine which candidates it will prioritize. Before 2020, the network used a formula that measured serum creatinine concentrations to assess a patient’s estimated glomerular filtration rate—the best-known measure of whether a patient has chronic kidney disease. Since black patients typically have higher serum creatinine concentrations than nonblacks with the same kidney function, the formula had applied an adjustment for black patients to ensure a more precise GFR estimate.

Activists in the wake of George Floyd’s death claimed that the formula’s adjustment was racist. This prompted the National Kidney Foundation and the American Society of Nephrology to create a task force to “reassess inclusion of race in the estimation of glomerular filtration rate.” The task force decided to nix the racial adjustment and set to work choosing a new formula that would not take race into account, which it released in 2021.

In December 2022, the board of UNOS’s transplant system issued a directive requiring all transplant centers to apply retroactively the new formula to determine black patients’ spots on the national waitlist. Last December, the network announced the results of its application of the new formula. Removing the racial adjustments had moved the waitlist’s more than 6,100 black patients up by an average of 1.7 years, with just over 500 receiving a transplant. Of course, this meant that some nonblack patients were correspondingly pushed back in line.

The Prophets: D.A. Henderson Years before Covid, the scientist credited with eradicating smallpox warned against shutting down the world to combat an epidemic. Joe Nocera

https://www.thefp.com/p/the-prophets-da-henderson?utm_campaign=email-post&r=8t06w&utm_source=substack&utm_medium=email

Welcome back to The Prophets, our new Saturday series about fascinating people from the past who predicted our current moment and make our world more understandable today.

Last week, we showed how civil rights hero Bayard Rustin predicted the rise of identity politics and affirmative action—and how they would divide us today. Today, Joe Nocera spotlights D.A. Henderson, the epidemiologist who warned that pandemic lockdowns won’t stop a disease, but could instead lead to a public health disaster. Bari Weiss

“In 2006, ten years before his death at the age of 87, the legendary epidemiologist D.A. Henderson laid out a plan for how public health officials should respond to a major influenza pandemic. It was published in a small journal that focused mainly on bioterrorism—and was quickly forgotten.

As it turns out, that paper, titled “Disease Mitigation Measures in the Control of Pandemic Influenza,” was Henderson’s prescient bequest to the future. If we had followed his advice, our country—indeed, our world—could have avoided its disastrous response to Covid. 

This month marks the four-year anniversary of lockdowns on a global scale. And though the pandemic has passed, its consequences live on. The lockdowns embraced by the U.S. public-health establishment meant that millions of young people had their education and social development disrupted, or left school for good. Mental health problems rose substantially. So did incidents of domestic violence and overdose deaths.

It didn’t have to be that way. 

Joel Zinberg A Solution in Search of a Problem President Biden’s promise to expand drug-price controls will imperil supply and innovation.

https://media5.manhattan-institute.org/iiif/2/wp-content%2Fuploads%2Fsites%2F5%2Fdrug-price-controls.jpg/full/!99999,960/0/default.jpg

In his State of the Union address, President Biden touted the drug-price controls in his Inflation Reduction Act (IRA). Though the price controls have yet to take effect, Biden proposed expanding these measures, which threaten to destroy pharmaceutical innovation and harm the nation’s health.

The IRA’s drug-price controls are a solution in search of a problem. Two years ago, the Congressional Budget Office (CBO) found that per capita prescription-drug spending in real terms had fallen as a percentage of total spending on health care since the mid-2000s. Retail prescription drug prices have gone up at a slower rate than have hospital prices and health-care prices generally. According to researchers at the health-care data group IQVIA, U.S. drug spending is lower as a percentage of national health expenditures than the average drug-spending share across 11 developed countries.

While price-control proponents focus on drugs’ high list prices, the average net price of a prescription—the amount that users actually paid after subtracting manufacturers’ discounts and rebates—has been falling, according to CBO. This reflects the increased use of generic drugs, which cost far less than name-brand pharmaceuticals and now account for nine out of ten prescriptions. In fact, U.S. patients use more generics and pay less for them (16 percent less, on average) than do patients in other developed countries.

Safety and effectiveness of Covid vaccines were exaggerated in publication of key studies Raphael Lataster, PHD

https://okaythennews.substack.com/p/science-summary-covid-19-vaccines?utm_source=substack&utm_campaign=post_embed&utm_medium=email

An unofficial series of 4 crucially important medical journal articles (JECP4), 2 by me, appearing in major academic publisher Wiley’s Journal of Evaluation in Clinical Practice reveals that claims made about COVID-19 vaccines’ effectiveness and safety were exaggerated in the clinical trials and observational studies, which significantly impacts risk-benefit analyses. Also discussed are the concerning topics of myocarditis, with evidence indicating that this one adverse effect alone means that the risks outweigh the benefits in the young and healthy; and perceived negative effectiveness, which indicates that the vaccines increase the chance of COVID-19 infection/hospitalisation/death, to say nothing about other adverse effects.

Whilst already planning for a holiday overseas on the advice of my treating team, I fortuitously was invited to share my research and discuss my ongoing persecution alongside brilliant and courageous doctors, scientists, academics, lawyers, and activists, such as Dr Robert Malone, who declared this research to be “excellent”, and “some of the best work, academically, in reevaluating the data”, culminating in an invitation to testify for US Senator Ron Johnson. So for those who are here because of the associated videos, and anyone else interested in this topic, please enjoy this much more detailed summary.

Why Americans No Longer Trust the Healthcare System By Brian C. Joondeph, M.D.

https://www.americanthinker.com/articles/2024/03/why_americans_no_longer_trust_the_healthcare_system.html

Trust is foundational in relationships, whether between individuals or between individuals and institutions. A Gallup survey from last summer found, “Americans’ faith in major societal institutions hasn’t improved over the past year following a slump in public confidence in 2022.”

Notable other examples where surprisingly few Americans have “a great deal or quite a lot of confidence” in major institutions include Congress at 8%, big business and television news at 14%, and the criminal justice system at only 17%. The medical system fared slight better with 34% of Americans expressing confidence. But two thirds have lost trust.

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Doctors, hospitals, and healthcare systems used to be held in high esteem, but no more. Aren’t these the “experts” in white coats? What happened to that trust? Why do only 1 in 3 Americans trust what was once a sacred healing profession?

Rasmussen Reports recently asked American adults three questions

On health-related issues, how much trust do you have in experts who give advice on TV and other media?
In terms of your own health-care decisions, which is closer to your attitude, that it’s safe to trust advice from experts, or that it’s important to do your own research?
Thinking back on the COVID-19 pandemic, were most of the experts basically right or wrong?

Not surprisingly, trust is low. What is interesting is the partisan divide, with Democrats far more trusting in medical instructions than Republicans.

Leading California Hospitals Are Becoming a ‘Battlefield’ as Jewish Patients, Doctors Face Surging Antisemitism ‘The halls of medicine should be to treat humanity,’ one doctor tells the Sun, not fodder for political protest. M.J.Koch

https://www.nysun.com/article/leading-california-hospitals-are-becoming-a-battlefield-as-jewish-patients-doctors-face-surging-antisemitism

Brazen acts of antisemitism are tearing apart one of the top hospitals in the nation at the University of California San Francisco, with Jewish doctors being bullied, cancer patients encountering antisemitic graffiti, and one pregnant Israeli woman reportedly being refused care. 

The university has seen a surge in antisemitism at its sprawling network of seven Bay Area hospitals and on the social media posts of its most prominent doctors since Hamas’s October 7 attacks on Israel. Jewish doctors tell the Sun that they are “paranoid” about speaking out on the issue despite a growing number of complaints from patients regarding their providers’ views on the Israel-Hamas war.

Most recently, graffiti invoking the language of the Holocaust was found on two signs near UCSF’s cancer center at its Mission Bay campus. The chancellor of UCSF, Sam Hawgood, condemned the incident in a statement on Monday and said that the local police are investigating it.

In another striking instance, a whiteboard was wheeled out and positioned at the entrance to a UCSF cancer building. It bore the words “Free Palestine from Nazi Zionist Schwein,” invoking the German word meaning “pig.”

In a physician lounge was a sign that said “stop bombing hospitals,” one UCSF doctor, who asked for anonymity given the sensitive nature of the situation, tells the Sun. He also noticed that a UCSF resident had a phone case with a Palestinian flag on it and the words, “warning, you are on Palestinian land.”

Richard T. Bosshardt Not Cutting It Bad policies are leaving the next generation of surgeons unprepared.

https://www.city-journal.org/article/bad-policies-leaving-next-generation-of-surgeons-unprepared

What is going on in surgery? Why are young surgeons are coming out of residency programs unprepared for clinical practice? A 2013 Annals of Surgery report revealed that 40 percent of surgical residents lacked confidence to practice independently after five years of training, the typical length of a full general-surgery residency. According to the same report, one in five surveyed program directors “felt that new fellows arrived unprepared for the operating room,” and program directors deemed 66 percent of new fellows incapable of operating unsupervised for more than 30 minutes in a major surgery.

While these statistics are frightening, that report is 11 years old. Have things gotten better since? Judging by more recent reports and my conversations with peers, they have not, and in fact, have probably gotten worse. Surgeons I have recently spoken to have observed that too many young surgeons are poorly prepared and need remedial help, such as operating with a more experienced surgeon before they can be trusted to operate on their own. The young surgeons themselves seem to realize their inadequate preparation, as nearly 80 percent of post-general-training surgeons pursue a one or two-year fellowship in a subspecialty, which for some may be a way to get more surgical experience and put off entering general practice.

One possible explanation for young surgeons’ lack of preparation stems from the American Council on Graduate Medical Education’s 2003 decision to limit residents in training to 80-hour work weeks and no more than 24 consecutive work hours. For surgery residents, fewer work hours means less time spent caring for patients and performing surgeries. Only with time and repetition do surgical residents develop the requisite cognitive and technical skills necessary to learn sound surgical judgement—knowing when to operate and what operation to do—and how to operate safely under all circumstances. The hour reductions also have resulted in less continuity, as residents hand off patients to one another, diminishing residents’ sense of responsibility for patient care.

The Truth is Coming Out

https://johnhabelesmd.substack.com/?utm_campaign=email-home&r=8t06w&utm_source=substack

These are tough times for the “great reset.” The broad and global EV market is failing, mRNA shots are in disrepute, the reality of surveillance and censorship is getting media attention, and public anger at the whole of the wild push to wreck freedom and rights is rising quickly all over the world. 

The more time has passed since lockdowns, the more clear it becomes that this was part of a much larger agenda. But here’s the problem. They are not giving up, not even close. The reason there have been no apologies is that they are not sorry. They are more determined than ever. 

The one path of resistance is the creation of new information infrastructures such as Brownstone Institute. It’s our hope to shine a light on truth, protect the rights of serious research and commentary, and use every freedom we have left to highlight genuine science, logic, and enlightenment ideals. 

In passing, our supper clubs are now selling out completely. This has to be a good sign! 

We deeply appreciate your support. Given the odds, we certainly need it! 

Here is some content since our last email:

Pfizer Never Stops Gaslighting Us By Lori Weintz. Pfizer’s cheery Super Bowl ad cannot change the fact that they never tested their BNT162b2 vaccine during clinical trials to see if it prevented transmission of Covid-19. Nor did Pfizer stop distribution when 90 days into the vaccination campaign, there had already been 1,123 vaccine-related deaths, and over 40,000 vaccine injuries.  

Liz Peek: Pfizer Super Bowl ad proves just how damaging Biden’s COVID response has been for America

https://thehill.com/opinion/healthcare/4470475-pfizer-super-bowl-ad-proves-just-how-damaging-bidens-covid-response-has-been-for-america/

Why did Pfizer spend millions of dollars on a Super Bowl ad? And why are they paying Travis Kelce $20 million to act as their vaccine spokesperson?  

Because their reputation — and the reputation of America’s medical authorities — needs serious rehabilitation. A Gallup survey conducted last fall found only 18 percent of Americans have a very or somewhat positive view of the pharmaceutical industry, down from 25 percent in 2022. That’s a worse rating than any other industry group but retail.   

This is one of the most damaging leftovers of the Biden presidency.   

Joe Biden’s authoritarian approach to managing the COVID-19 outbreak, forcing all workplaces of 100 or more people to require the vaccine or regularly test their employees and the censorship of opposing views on vaccine side effects and on treatments, not only trampled on Americans’ rights — it may have led to preventable deaths.  

Nothing could have highlighted Americans’ distrust of the pharmaceutical industry more starkly than the Pfizer ad, which aimed to rebuild not only its brand but general attitudes toward medicine. It’s hard to imagine a world where a leading drug-maker feels the need to remind people that science has led to life-saving breakthroughs like the invention of penicillin and treatments for cancer, yet here we are. 

The ad, wedged between promotions for beer and donuts and other more conventional fare, combined a jazzy upbeat tune with pictures of the founders of Pfizer, seeming to place them in the same scientific galaxy as Sir Isaac Newton and Copernicus, who came alive in their portraits long enough to join in the fun. It was memorable, mainly because it seemed so out of place. 

Pfizer’s problem is, first, that sales of its COVID-19 vaccines and therapies have cratered as the disease has faded. But more important, Pfizer is dealing with backlash against Biden’s heavy-handed dictates about vaccines.  

MASSIVE Academic Fraud, Scientific Exposed Ben Bartee

https://pjmedia.com/benbartee/2024/02/14/massive-academic-fraud-scientific-exposed-n4926447

It turns out that the High Priests of The Science™ are just as susceptible to the earthly temptation to engage in corruption as the lowly peasants they rule over.

Via Stat News (emphasis added):

There was a time when an allegation of data mishandling, scientific misconduct, or just a technical error felt like a crisis to Barrett Rollins, an oncologist and research integrity officer at Dana-Farber Cancer Institute. Now, it’s just another Tuesday.

The renowned cancer treatment and research center is in the midst of a lengthy review of possible discrepancies involving around 60 papers co-authored by four of its top researchers over a period of over 15 years, including CEO Laurie Glimcher and COO William Hahn. And it’s hardly alone. Over the past decade, the number of research misconduct allegations reported to the National Institutes of Health has more than doubled, climbing from 74 in 2013 to 169 in 2022. And scientific sleuths are finding plenty of other problems that don’t always qualify as outright misconduct.

Via American Council on Science and Health (emphasis added):

According to a 2022 study in the Netherlands, over the last three years, one in two researchers had engaged frequently in at least one “questionable research practice,” with “not submitting or resubmitting valid negative studies for publication” being the most common practice. The fields of life and medical sciences had the highest prevalence (55.3%) of engaging in questionable practices compared to other disciplines.

Never publishing studies that show unfavorable results — or else not conducting studies in the first place likely to show unfavorable results even when doing the research would be a valuable addition to the general body of scientific knowledge — is likely a far more common corrupt practice than actively rigging of studies themselves, although that happens often as well, as seen in the case of the Pfizer COVID shots, among numerous other forms of data-rigging activity to push them through the regulatory process, for which no Pfizer scientist or executive has yet been punished.

                

(Maybe if Congress holds a few more sharp-tongued hearings on COVID malfeasance, we can finally get some action on the prosecution front. But that’s a story for another day.)