https://www.city-journal.org/article/kidneys-dont-see-color
On March 16, 2024, surgeons at Massachusetts General Hospital transplanted a genetically modified pig kidney into a 62-year-old man suffering from end-stage kidney disease. The groundbreaking operation was, among much else, a refutation of the STEM diversity crusade, which threatens the medical progress that lay behind the landmark procedure.
Transplant recipient Richard Slayman had endured the usual debilitating effects of kidney failure for years. Healthy kidneys filter toxins and excess fluids from blood and excrete those waste products as urine. When kidneys fail, if no donated human kidney is available to replace them, patients spend hours a week hooked up to a dialysis machine that filters their blood mechanically. Slayman had already spent seven years on dialysis before receiving a human kidney in 2018. That transplanted kidney itself faltered, however, and by 2023, Slayman was back on dialysis. This time, though, he required biweekly visits to the hospital to keep his blood vessels open. He developed congestive heart failure. And he rejoined the more than 100,000 Americans waiting, often futilely and fatally, for a human kidney.
If Slayman’s new pig kidney continues to function, the capacity to transplant animal organs successfully into humans (a process known as xenotransplantation) will be as significant as curing cancer, says nephrologist Stanley Goldfarb. Getting to this point required 125 years of scientific creativity and an ever more complex understanding of molecular biology. None of that development had anything to do with racial identity.
Slayman’s genetically modified pig kidney represents a return of sorts to the origins of transplant science. When surgeons started contemplating organ transplants in the early twentieth century, they initially focused on organs from other mammals, since harvesting human organs was considered problematic at best. The French surgeon Alexis Carrel began a series of transplant experiments on dogs after discovering how to connect arteries to arteries and how to widen narrowed vessels—prerequisites to organ transplantation. For the next several decades, surgeons in France, Germany, Russia, and the U.S. transplanted goat, sheep, and monkey kidneys into dying human patients, but the organs (and patients) quickly failed. It would take the evolution of another branch of medical science—immunology—to understand why.